Reaction profile

The FDA adverse-event record for piloerection

171 FDA adverse-event reports reference piloerection (VeDDRA 910). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1121 of 2,481
by report volume (all reactions)
171
reports citing this reaction
2.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Piloerection has 171 reports now versus 170 in that prior snapshot: 1 more (0.6%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Piloerection changes

FDA AER · VeDDRA plate

Code 910 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 171 reports
  • DEATH-LOW 2.9%
  • MID-PACK #1121/2481
  • PHOTO-FINISH Abrasion
  • SPECIES-DOG Dog · 154
  • DRUG-LEAD Phenylpropanolami… · 68
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abrasion (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Piloerection

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abrasion · near171Hypoxia · near171Myositis · near171Piloerection · this reaction171Defecation related to… · near170Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Piloerection

Piloerection: low death-coded share in the FDA AER plate

Signature read: Piloerection's 2.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 5 of 171 reports (2.9% of named reports). Nearest volume peer: Abrasion (±0 reports). Lead species Dog (154). Lead co-reported drug Phenylpropanolamine Hcl (68).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Phenylpropanolamine Hcl appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 154
Cat 14
Ferret 1
Cattle 1
Other 1

Breeds Most Affected

Retriever - Labrador 38
Crossbred Canine/dog 21
Domestic Shorthair 12
Boxer (German Boxer) 11
Chihuahua 10
Shepherd Dog - German 9
Weimaraner 6
Terrier - Bull - American Pit 6
Doberman Pinscher 5
Ridgeback - Rhodesian 4

Associated Drugs

Phenylpropanolamine Hcl 68
Phenylpropropanolamine Hcl 29
Phenylpropanolamine 13
Milbemycin Oxime + Spinosad 8
Phenylpropanolamine Hydrochloride 8
Melarsomine Dihydrochloride 6
Acepromazine 5
Hydrogen Peroxide 4
Diphenhydramine 4
Tramadol 3
Butorphanol 3
Isoflurane 3
Fluralaner Chew Tablets 3
Sarolaner 3
Famotidine 3
Oclacitinib Maleate 3
Spinosad 2
Imidacloprid + Moxidectin 2
Meloxicam 2
Ketamine 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Piloerection, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (171 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Piloerection (#1121 of 2,481 by report volume); death-coded 2.9%. PlainBreed reaction plate · death-coded share stamp 2.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →