Facial nerve disorder

Verify with FDA CVM →

VeDDRA Code: 1148

138 adverse event reports referencing this reaction

138
Total Reports
23
Deaths
1670.0%
Death Rate

Species Most Affected

Dog 121
Cat 12
Horse 3
Ferret 2

Breeds Most Affected

Retriever - Golden 13
Crossbred Canine/dog 12
Beagle 9
Retriever - Labrador 9
Boxer (German Boxer) 7
Domestic Shorthair 7
Chihuahua 7
Spaniel - King Charles Cavalier 6
Shepherd Dog - German 5
Spaniel (unspecified) 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 21
Prednisone 13
Trilostane 12
Carprofen 11
Maropitant Citrate 11
Fluralaner Chew Tablets 9
Milbemycin Oxime + Spinosad 8
Gabapentin 8
Oclacitinib Maleate 7
Afoxolaner 7
Fluralaner 6
Cyclosporine 6
Cefovecin 5
Moxidectin 5
Enrofloxacin 5
Sarolaner 5
Meclizine 5
Bedinvetmab 5
Selamectin 4
Marbofloxacin 4

Data Summary

Metric Value
Total reports referencing reaction 138
Reports with fatal outcome 23
Case-fatality rate (reported events) 1670.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1148.

Facial nerve disorder Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 138 adverse event reports that reference Facial nerve disorder as a reaction term, including 23 reports with a death outcome — a 1670.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1148, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Facial nerve disorder appears most frequently in reports for Dog (121 reports), Cat (12 reports), Horse (3 reports) — with Dog dominating at 121 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Golden (13), Crossbred Canine/dog (12), Beagle (9). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Facial nerve disorder are Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (21 reports), Prednisone (13 reports), Trilostane (12 reports), Carprofen (11 reports), with Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appearing alongside this reaction in 21 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial