Reaction profile

The FDA adverse-event record for decreased intra-ocular pressure

52 FDA reports name decreased intra-ocular pressure, a lower-volume reaction in the CVM extract (VeDDRA 2463). Plate stamps and neighbourhood peers follow.

#1715 of 2,481
by report volume (all reactions)
52
reports citing this reaction
11.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased intra-ocular pressure has 52 reports now versus 51 in that prior snapshot: 1 more (2.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased intra-ocular pressure changes

FDA AER · VeDDRA plate

Code 2463 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 52 reports
  • DEATH-ELEV 11.5%
  • MID-PACK #1715/2481
  • PHOTO-FINISH Hypersensitivity to p…
  • SPECIES-DOG Dog · 46
  • DRUG-LEAD Maropitant Citrate · 12
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hypersensitivity to pain (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Decreased intra-ocular pressure

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Decreased intra-ocula… · thi…52Hypersensitivity to p… · near52Impurity · near52Injection site haemor… · near52Intestinal haemorrhage · near52Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased intra-ocular pressure

What the FDA AER plate says about Decreased intra-ocular pressure

Signature read: 6 death-coded reports is a thin tail count for Decreased intra-ocular pressure in the CVM extract. Report volume is lower-third scale: 52 named reports in the openFDA extract. 6 of 52 reports were death-coded (11.5% of named reports, not a population mortality rate). Nearest volume peer: Hypersensitivity to pain (±0 reports). Lead species Dog (46). Lead co-reported drug Maropitant Citrate (12).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 46
Cat 6

Breeds Most Affected

Crossbred Canine/dog 7
Retriever - Labrador 7
Domestic Shorthair 4
Chihuahua 4
Shepherd Dog - Australian 3
Poodle - Standard 2
Collie - Border 2
Terrier - Boston 2
Retriever - Golden 2
Terrier - Rat 2

Associated Drugs

Maropitant Citrate 12
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Prednisone 7
Gabapentin 7
Buprenorphine 6
Robenacoxib 5
Meloxicam 4
Ofloxacin 4
Eye Lubricant 3
Oclacitinib 3
Ear Cleaner 3
Dexmedetomidine 3
Leptospirosis Vaccine 3
Bordetella Vaccine 3
Bedinvetmab 3
Atipamezole 3
Fluid Therapy 3
Trilostane 3
Fluralaner Chew Tablets 2
Afoxolaner 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased intra-ocular pressure, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (52 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased intra-ocular pressure (#1715 of 2,481 by report volume); death-coded 11.5%. PlainBreed reaction plate · death-coded report count stamp 6 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →