Reaction profile

The FDA adverse-event record for decreased intra-ocular pressure

48 FDA adverse-event reports reference decreased intra-ocular pressure (VeDDRA 2463). See the species, breeds, and drugs most associated with it below.

48
reports citing this reaction
12.5%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
48
Total Reports
6
Deaths
12.5%
Death Rate

Species Most Affected

Dog 42
Cat 6

Breeds Most Affected

Crossbred Canine/dog 7
Retriever - Labrador 7
Domestic Shorthair 4
Shepherd Dog - Australian 3
Chihuahua 3
Poodle - Standard 2
Collie - Border 2
Terrier - Boston 2
Retriever - Golden 2
Terrier - Rat 2

Associated Drugs

Maropitant Citrate 12
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Prednisone 7
Buprenorphine 6
Gabapentin 6
Robenacoxib 5
Meloxicam 4
Ofloxacin 4
Eye Lubricant 3
Oclacitinib 3
Ear Cleaner 3
Dexmedetomidine 3
Leptospirosis Vaccine 3
Bordetella Vaccine 3
Atipamezole 3
Fluralaner Chew Tablets 2
Afoxolaner 2
Bupivacaine 2
Milbemycin Oxime + Praziquantel 2
Lotilaner 2

Decreased intra-ocular pressure Reaction Insights

48 reports name Decreased intra-ocular pressure; 6 recorded a death outcome (12.5% of reported events, not a population-level mortality rate). VeDDRA code: 2463.

By species: Dog (42 reports), Cat (6 reports). By breed: Crossbred Canine/dog (7), Retriever - Labrador (7), Domestic Shorthair (4).

Most co-reported drugs: Maropitant Citrate (12 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (9 reports), Prednisone (7 reports), Buprenorphine (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.