Other blood disorder NOS

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VeDDRA Code: 1666

251 adverse event reports referencing this reaction

251
Total Reports
78
Deaths
3110.0%
Death Rate

Species Most Affected

Dog 205
Cat 38
Horse 4
Cattle 2
Human 1
Other Birds 1

Breeds Most Affected

Retriever - Labrador 22
Domestic Shorthair 21
Retriever - Golden 12
Crossbred Canine/dog 10
Shepherd Dog - German 9
Chihuahua 8
Shih Tzu 8
Pit Bull 7
Shepherd Dog - Australian 7
Terrier - Yorkshire 6

Associated Drugs

Milbemycin Oxime + Spinosad 42
Oclacitinib Maleate 30
Trilostane 20
Spinosad 19
Carprofen 18
Maropitant Citrate 16
Moxidectin 11
Afoxolaner 11
Bedinvetmab 10
Buprenorphine 9
Ivermectin 8
Metronidazole 8
Polysulfated Glycosaminoglycan 8
Milbemycin Oxime + Praziquantel 8
Prednisone 7
Enrofloxacin 7
Gabapentin 7
Pyrantel Pamoate;Sarolaner 7
Dexamethasone 6
Meloxicam 6

Data Summary

Metric Value
Total reports referencing reaction 251
Reports with fatal outcome 78
Case-fatality rate (reported events) 3110.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1666.

Other blood disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 251 adverse event reports that reference Other blood disorder NOS as a reaction term, including 78 reports with a death outcome — a 3110.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1666, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Other blood disorder NOS appears most frequently in reports for Dog (205 reports), Cat (38 reports), Horse (4 reports) — with Dog dominating at 205 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (22), Domestic Shorthair (21), Retriever - Golden (12). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Other blood disorder NOS are Milbemycin Oxime + Spinosad (42 reports), Oclacitinib Maleate (30 reports), Trilostane (20 reports), Spinosad (19 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 42 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial