Reaction profile

The FDA adverse-event record for lip licking

896 FDA adverse-event reports reference lip licking (VeDDRA 2096). See the species, breeds, and drugs most associated with it below.

896
reports citing this reaction
3.1%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
896
Total Reports
28
Deaths
3.1%
Death Rate

Species Most Affected

Dog 729
Cat 153
Horse 14

Breeds Most Affected

Domestic Shorthair 92
Retriever - Labrador 71
Crossbred Canine/dog 54
Chihuahua 45
Terrier - Yorkshire 33
Retriever - Golden 29
Maltese 27
Pit Bull 25
Shih Tzu 22
Shepherd Dog - German 20

Associated Drugs

Milbemycin Oxime + Spinosad 175
Afoxolaner 61
Imidacloprid + Moxidectin 45
Fluralaner Chew Tablets 41
Selamectin 35
Ivermectin + Pyrantel As Pamoate Salt 35
Maropitant Citrate 35
Fluralaner 13.64% 12-Week Chew 31
Oclacitinib Maleate 29
Carprofen 28
Fluralaner Spot-On Solution 27
Sarolaner 26
Pyrantel Pamoate;Sarolaner 26
Spinosad 25
Milbemycin Oxime + Praziquantel 24
Moxidectin 23
Emodepside + Praziquantel 17
Buprenorphine 15
Gabapentin 14
Bedinvetmab 14

Lip licking Reaction Insights

896 reports name Lip licking; 28 recorded a death outcome (3.1% of reported events, not a population-level mortality rate). VeDDRA code: 2096.

By species: Dog (729 reports), Cat (153 reports), Horse (14 reports). By breed: Domestic Shorthair (92), Retriever - Labrador (71), Crossbred Canine/dog (54).

Most co-reported drugs: Milbemycin Oxime + Spinosad (175 reports), Afoxolaner (61 reports), Imidacloprid + Moxidectin (45 reports), Fluralaner Chew Tablets (41 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.