Reaction profile

The FDA adverse-event record for lip licking

928 FDA reports name lip licking, a high-volume reaction in the CVM extract (VeDDRA 2096). Plate stamps and neighbourhood peers follow.

#415 of 2,481
by report volume (all reactions)
928
reports citing this reaction
3.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lip licking has 928 reports now versus 910 in that prior snapshot: 18 more (2.0%).

Report change
+18
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lip licking changes

FDA AER · VeDDRA plate

Code 2096 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 928 reports
  • DEATH-LOW 3.1%
  • UPPER-Q #415/2481
  • PHOTO-FINISH Lymphadenopathy
  • SPECIES-DOG Dog · 750
  • DRUG-LEAD Milbemycin Oxime… · 176
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lymphadenopathy (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Lip licking

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Lip licking · this reaction928Lymphadenopathy · near928Hyperalbuminaemia · near927Reduced responses · near924Knuckling · near923Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lip licking

Lip licking: low death-coded share in the FDA AER plate

Signature read: 928 reports place Lip licking in the upper third of FDA AER volume (#415 of 2,481). Report volume is upper-third scale: 928 named reports in the openFDA extract. Death-coded share is lower-third: 29 of 928 reports (3.1% of named reports). Nearest volume peer: Lymphadenopathy (±0 reports). Lead species Dog (750). Lead co-reported drug Milbemycin Oxime + Spinosad (176).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 750
Cat 161
Horse 17

Breeds Most Affected

Domestic Shorthair 99
Retriever - Labrador 72
Crossbred Canine/dog 55
Chihuahua 49
Terrier - Yorkshire 33
Retriever - Golden 29
Maltese 29
Pit Bull 25
Shih Tzu 23
Shepherd Dog - German 21

Associated Drugs

Milbemycin Oxime + Spinosad 176
Afoxolaner 64
Imidacloprid + Moxidectin 45
Fluralaner Chew Tablets 41
Maropitant Citrate 36
Selamectin 35
Ivermectin + Pyrantel As Pamoate Salt 35
Fluralaner 13.64% 12-Week Chew 35
Oclacitinib Maleate 31
Carprofen 28
Fluralaner Spot-On Solution 28
Milbemycin Oxime + Praziquantel 27
Sarolaner 27
Pyrantel Pamoate;Sarolaner 27
Spinosad 25
Moxidectin 24
Emodepside + Praziquantel 18
Buprenorphine 16
Gabapentin 16
Bedinvetmab 16

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lip licking, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (928 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lip licking (#415 of 2,481 by report volume); death-coded 3.1%. PlainBreed reaction plate · report volume stamp 928 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →