Reaction profile

The FDA adverse-event record for poor peripheral circulation

45 FDA reports name poor peripheral circulation, a lower-volume reaction in the CVM extract (VeDDRA 1702). Plate stamps and neighbourhood peers follow.

#1798 of 2,481
by report volume (all reactions)
45
reports citing this reaction
77.8%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Poor peripheral circulation has 45 reports now versus 45 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Poor peripheral circulation changes

FDA AER · VeDDRA plate

Code 1702 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 45 reports
  • DEATH-HOT 77.8%
  • MID-PACK #1798/2481
  • PHOTO-FINISH Application site disc…
  • SPECIES-DOG Dog · 29
  • DRUG-LEAD Deracoxib · 11
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site discharge NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Poor peripheral circulation

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site disc… · near45Buccal irritation · near45Chest tightness · near45Flaccid paralysis · near45Poor peripheral circu… · thi…45Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Poor peripheral circulation

Poor peripheral circulation: high death-coded share in the FDA AER plate

Signature read: Poor peripheral circulation's 77.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 45 named reports in the openFDA extract. Death-coded share is upper-third: 35 of 45 reports (77.8% of named reports). Nearest volume peer: Application site discharge NOS (±0 reports). Lead species Dog (29). Lead co-reported drug Deracoxib (11).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 29
Cat 10
Horse 4
Human 2

Breeds Most Affected

Retriever - Labrador 6
Domestic Shorthair 5
Unknown 3
Terrier - Yorkshire 2
Siamese 2
Crossbred Canine/dog 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Poodle - Standard 2
Thoroughbred 2
Pug 2

Associated Drugs

Deracoxib 11
Milbemycin Oxime + Spinosad 6
Carprofen 5
Robenacoxib 3
Trilostane 3
Spinosad 3
Tramadol 3
Polysulfated Glycosaminoglycan 3
Desoxycorticosterone Pivalate 2
Fipronil 2
Cyclosporine A 2
Buprenorphine 2
Lufenuron + Milbemycin Oxime 2
Mirtazapine 1
Maropitant Injection 1
Maropitant Tablets 1
Alprazolam 1
Ivermectin/Pyrantel 1
Prednisone 1
Melarsomine Dihydrochloride Injection 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Poor peripheral circulation (#1798 of 2,481 by report volume); death-coded 77.8%. PlainBreed reaction plate · death-coded share stamp 77.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →