Reaction profile

The FDA adverse-event record for gastric bloat

138 FDA adverse-event reports reference gastric bloat (VeDDRA 1090). See the species, breeds, and drugs most associated with it below.

138
reports citing this reaction
44.2%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
138
Total Reports
61
Deaths
44.2%
Death Rate

Species Most Affected

Dog 116
Cattle 9
Cat 7
Horse 4
Other Canids 1
Sheep 1

Breeds Most Affected

Retriever - Labrador 19
Deutsche Dogge, Great Dane 13
Crossbred Canine/dog 7
Shepherd Dog - German 7
Mastiff 4
Shepherd Dog - Australian 4
Boxer (German Boxer) 4
Holstein-Friesian also known as Holstein 4
Saint Bernard Dog 3
Bulldog 3

Associated Drugs

Milbemycin Oxime + Spinosad 15
Carprofen 11
Monensin Sodium 9
Milbemycin Oxime + Praziquantel 9
Spinosad 7
Cyclosporine 7
Bedinvetmab 6
Ivermectin + Pyrantel As Pamoate Salt 5
Afoxolaner 5
Oclacitinib Maleate 5
Moxidectin 4
Fluralaner Chew Tablets 4
Pyrantel Pamoate;Sarolaner 4
Gabapentin 4
Robenacoxib 4
Firocoxib 227 Mg Chewable 3
Isoflurane 3
Deracoxib 3
Ivermectin 3
Butorphanol 3

Gastric bloat Reaction Insights

138 reports name Gastric bloat; 61 recorded a death outcome (44.2% of reported events, not a population-level mortality rate). VeDDRA code: 1090.

By species: Dog (116 reports), Cattle (9 reports), Cat (7 reports). By breed: Retriever - Labrador (19), Deutsche Dogge, Great Dane (13), Crossbred Canine/dog (7).

Most co-reported drugs: Milbemycin Oxime + Spinosad (15 reports), Carprofen (11 reports), Monensin Sodium (9 reports), Milbemycin Oxime + Praziquantel (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.