Injection site pyoderma

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VeDDRA Code: 99

13 adverse event reports referencing this reaction

13
Total Reports
1
Deaths
770.0%
Death Rate

Species Most Affected

Dog 11
Cattle 1
Cat 1

Breeds Most Affected

Retriever - Golden 2
Spaniel - Cocker American 1
Boxer (German Boxer) 1
Terrier - Yorkshire 1
Cattle (other) 1
Beagle 1
Poodle (unspecified) 1
Turkish Angora 1
Akbash Dog 1
Bulldog - French 1

Associated Drugs

Moxidectin 3
Vaccine 2
Praziquantel 2
Prednisone 2
Glycosaminoglycan Polysulfate 1
Tramadol 1
Cefpodoxine Proxetil 1
Meloxicam 1
Acepromazine 1
Butorphanol 1
Ketamine 1
Midazolam 1
Isoflurane 1
Cefazolin 1
Maropitant 1
Oclacitinib Maleate 1
Anti-Il31 Mab Mcs Lot #1283563 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Recombitek C4 - 13D1.R1 1

Data Summary

Metric Value
Total reports referencing reaction 13
Reports with fatal outcome 1
Case-fatality rate (reported events) 770.0%
Species observed 3
Breeds observed 12
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99.

Injection site pyoderma Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 13 adverse event reports that reference Injection site pyoderma as a reaction term, including 1 reports with a death outcome — a 770.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Injection site pyoderma appears most frequently in reports for Dog (11 reports), Cattle (1 reports), Cat (1 reports) — with Dog dominating at 11 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Golden (2), Spaniel - Cocker American (1), Boxer (German Boxer) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Injection site pyoderma are Moxidectin (3 reports), Vaccine (2 reports), Praziquantel (2 reports), Prednisone (2 reports), with Moxidectin appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial