Reaction profile

The FDA adverse-event record for dysphonia

Name: Dysphonia - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

10 FDA reports name dysphonia, a lower-volume reaction in the CVM extract (VeDDRA 1268). Plate stamps and neighbourhood peers follow.

#2452 of 2,481
by report volume (all reactions): 10
reports citing this reaction: 10.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

FDA AER · VeDDRA plate

Code 1268 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-MID · BOOK-FULL

VOL-TRACE 10 reports
DEATH-ELEV 10.0%
BOTTOM-DECILE #2452/2481
PHOTO-FINISH Anoxia
SPECIES-DOG Dog · 7
DRUG-LEAD Lotilaner · 8
DESK-MID 6 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Dysphonia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Dysphonia

What the FDA AER plate says about Dysphonia

Signature read: 10 reports place Dysphonia in the lower third of FDA AER volume (#2452 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. 1 of 10 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (7). Lead co-reported drug Lotilaner (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Lotilaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 7

Cat 3

Breeds Most Affected

Retriever - Labrador 4

Domestic Longhair 2

Spaniel - Springer (unspecified) 1

Shepherd Dog - Australian 1

Domestic Shorthair 1

Crossbred Canine/dog 1

Associated Drugs

Lotilaner 8

Bordetella Vaccine 3

Butorphanol 2

Ilunocitinib 2

Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Borrelia Burgdorferi Bacterin-Lepto Cani-Grippo-Ictero-Pomona Bacterial Extract 2

Canine Distemper + Adenovirus Type 2 + Coronavirus + Parainfluenza + Parvovirus Vaccine 2

Milbemycin Oxime + Lufenuron + Praziquantel 2

Canine Distemper Virus + Adenovirus Type 2 Parvovirus + Parainfluenza Virus + Leptospirosis 2

Lyme Vaccine 2

Rabies Vaccine 2

Microchip 2

Tobramycin Ophthalmic 2

Doxycycline 2

Carprofen 2

Fenbendazole 2

Omega-3 Fatty Acids 2

Skin Treatment (Unknown) 2

Tiletamine Hcl; Zolazapam Hcl 1

Fluralaner Spot-On Solution 1

Imidacloprid + Moxidectin 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dysphonia (#2452 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →