Reaction profile

The FDA adverse-event record for disorder of gastrointestinal flora

201 FDA adverse-event reports reference disorder of gastrointestinal flora (VeDDRA 2563). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1031 of 2,481
by report volume (all reactions)
201
reports citing this reaction
16.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Disorder of gastrointestinal flora has 201 reports now versus 197 in that prior snapshot: 4 more (2.0%).

Report change
+4
Death-coded reports
+1
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Disorder of gastrointestinal flora changes

FDA AER · VeDDRA plate

Code 2563 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 201 reports
  • DEATH-ELEV 16.4%
  • MID-PACK #1031/2481
  • PHOTO-FINISH Digestive tract haemo…
  • SPECIES-DOG Dog · 172
  • DRUG-LEAD Fluralaner Chew T… · 27
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Digestive tract haemorrhage NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Disorder of gastrointestinal flora

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Increased sexual inte… · near202Loss of voluntary mov… · near202Digestive tract haemo… · near201Disorder of gastroint… · thi…201Stillbirth · near201Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Disorder of gastrointestinal flora

What the FDA AER plate says about Disorder of gastrointestinal flora

Signature read: 33 death-coded reports is the most distinctive absolute-outcome stamp on Disorder of gastrointestinal flora. Report volume sits in the middle third of the reaction corpus. 33 of 201 reports were death-coded (16.4% of named reports, not a population mortality rate). Nearest volume peer: Digestive tract haemorrhage NOS (±0 reports). Lead species Dog (172). Lead co-reported drug Fluralaner Chew Tablets (27).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Fluralaner Chew Tablets appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 172
Cat 23
Cattle 1
Rabbit 1
Pig 1
Human 1
Fish 1
Horse 1

Breeds Most Affected

Retriever - Labrador 18
Domestic Shorthair 16
Dog (unknown) 13
Chihuahua 11
Retriever - Golden 10
Crossbred Canine/dog 8
Boxer (German Boxer) 7
Shepherd Dog - German 6
Shih Tzu 5
Terrier (unspecified) 4

Associated Drugs

Fluralaner Chew Tablets 27
Oclacitinib Maleate 22
Milbemycin Oxime + Praziquantel 18
Moxidectin 17
Maropitant Citrate 16
Carprofen 14
Pyrantel Pamoate;Sarolaner 14
Prednisone 11
Sarolaner 9
Insulin Injectable Vial 8
Trilostane 7
Grapiprant 7
Gabapentin 6
Milbemycin Oxime + Spinosad 6
Fluralaner 13.64% 12-Week Chew 6
Anti-Il31 Mab Mcs Lot #1283563 5
Fluralaner Spot-On Solution 5
Metronidazole 4
Maropitant 4
Buprenorphine 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Disorder of gastrointestinal flora, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (16.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Disorder of gastrointestinal flora (#1031 of 2,481 by report volume); death-coded 16.4%. PlainBreed reaction plate · death-coded report count stamp 33 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →