Liver abscess

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VeDDRA Code: 485

33 adverse event reports referencing this reaction

33
Total Reports
22
Deaths
6670.0%
Death Rate

Species Most Affected

Cattle 25
Dog 8

Breeds Most Affected

Holstein-Friesian also known as Holstein 7
Cattle (unknown) 7
Cattle (other) 4
Aberdeen Angus 4
Crossbred Bovine/Cattle 2
Collie - Border 2
Spitz - German Pomeranian 1
Shepherd Dog - German 1
Chihuahua 1
Weimaraner 1

Associated Drugs

Monensin Sodium 15
Tylosin Phosphate 7
Doramectin 7
Enrofloxacin 6
Tulathromycin 5
Estradiol,Trenbolone Acetate 5
Fenbendazole 5
Trenbolone Acetate + Estradiol 5
Ivermectin 4
Ractopamine Hydrochloride 3
Carprofen 3
Afoxolaner 3
Tildipirosin Injectable 3
Ceftiofur 3
Mycoplasma Bovis Bacterin 3
Tannin 3
Bovine Herpse + Virus Diarrhea + Parainfluenza 3 + Respiratory Syncytial Virus Vaccine + Killed Virus 3
Milbemycin Oxime + Spinosad 2
Trenbolone Acet/Estradiol Impl 2
Zeranol Implant 2

Data Summary

Metric Value
Total reports referencing reaction 33
Reports with fatal outcome 22
Case-fatality rate (reported events) 6670.0%
Species observed 2
Breeds observed 13
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 485.

Liver abscess Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 33 adverse event reports that reference Liver abscess as a reaction term, including 22 reports with a death outcome — a 6670.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 485, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Liver abscess appears most frequently in reports for Cattle (25 reports), Dog (8 reports) — with Cattle dominating at 25 entries. Within those species, the breeds most often named alongside this reaction are Holstein-Friesian also known as Holstein (7), Cattle (unknown) (7), Cattle (other) (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Liver abscess are Monensin Sodium (15 reports), Tylosin Phosphate (7 reports), Doramectin (7 reports), Enrofloxacin (6 reports), with Monensin Sodium appearing alongside this reaction in 15 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial