Reaction profile

The FDA adverse-event record for penile erection

25 FDA adverse-event reports reference penile erection (VeDDRA 2136). See the species, breeds, and drugs most associated with it below.

25
reports citing this reaction
8.0%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
25
Total Reports
2
Deaths
8.0%
Death Rate

Species Most Affected

Dog 22
Horse 2
Human 1

Breeds Most Affected

Retriever - Labrador 4
Shepherd Dog - German 2
Chihuahua 2
Dog (unknown) 1
Poodle - Toy 1
Horse (unknown) 1
Retriever - Golden 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Bichon Frise 1
Dachshund - Miniature 1

Associated Drugs

Oclacitinib Maleate 5
Milbemycin Oxime + Spinosad 4
Enrofloxacin 4
Glucosamine Hcl (Shellfish), Methylsulfonylmethane (Msm), Creatine Monohydrate, Boswellia Serrata Extract 3
Pergolide Mesylate 2
Afoxolaner 2
Gabapentin 2
Fluralaner Chew Tablets 2
Milbemycin Oxime 2
Bedinvetmab 2
Ivermectin + Pyrantel As Pamoate Salt 1
Cyclosporine A 1
Flumethrin-Imidacloprid 1
Maropitant Citrate 1
Buprenorphine 1
Methocarbamal 1
Probiotic 1
Unspecified Type Of Anesthesia 1
Intravenous Fluids 1
Injectable Famotidine 1

Penile erection Reaction Insights

25 reports name Penile erection; 2 recorded a death outcome (8.0% of reported events, not a population-level mortality rate). VeDDRA code: 2136.

By species: Dog (22 reports), Horse (2 reports), Human (1 reports). By breed: Retriever - Labrador (4), Shepherd Dog - German (2), Chihuahua (2).

Most co-reported drugs: Oclacitinib Maleate (5 reports), Milbemycin Oxime + Spinosad (4 reports), Enrofloxacin (4 reports), Glucosamine Hcl (Shellfish), Methylsulfonylmethane (Msm), Creatine Monohydrate, Boswellia Serrata Extract (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.