Vasculitis

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VeDDRA Code: 247

341 adverse event reports referencing this reaction

341
Total Reports
69
Deaths
2020.0%
Death Rate

Species Most Affected

Dog 283
Cat 35
Horse 15
Cattle 4
Human 3
Rabbit 1

Breeds Most Affected

Retriever - Labrador 23
Crossbred Canine/dog 23
Domestic Shorthair 22
Retriever - Golden 17
Chihuahua 16
Dog (unknown) 12
Terrier - Jack Russell 8
Pit Bull 8
Rottweiler 8
Boxer (German Boxer) 7

Associated Drugs

Carprofen 64
Maropitant Citrate 37
Moxidectin 26
Prednisone 24
Gabapentin 23
Milbemycin Oxime + Spinosad 18
Bedinvetmab 18
Metronidazole 15
Tramadol 15
Cefovecin 14
Enrofloxacin 14
Oclacitinib Maleate 13
Afoxolaner 13
Meloxicam 12
Buprenorphine 12
Famotidine 12
Diphenhydramine Hcl 11
Doxycycline 11
Dexamethasone 10
Fluralaner Chew Tablets 10

Data Summary

Metric Value
Total reports referencing reaction 341
Reports with fatal outcome 69
Case-fatality rate (reported events) 2020.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 247.

Vasculitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 341 adverse event reports that reference Vasculitis as a reaction term, including 69 reports with a death outcome — a 2020.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 247, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Vasculitis appears most frequently in reports for Dog (283 reports), Cat (35 reports), Horse (15 reports) — with Dog dominating at 283 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (23), Crossbred Canine/dog (23), Domestic Shorthair (22). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Vasculitis are Carprofen (64 reports), Maropitant Citrate (37 reports), Moxidectin (26 reports), Prednisone (24 reports), with Carprofen appearing alongside this reaction in 64 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial