Reaction profile

The FDA adverse-event record for unclassifiable adverse event

2,876 FDA reports name unclassifiable adverse event, a high-volume reaction in the CVM extract (VeDDRA 2190). Plate stamps and neighbourhood peers follow.

#164 of 2,481
by report volume (all reactions)
2,876
reports citing this reaction
8.1%
death-coded share
Human
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unclassifiable adverse event has 2,876 reports now versus 2,851 in that prior snapshot: 25 more (0.9%).

Report change
+25
Death-coded reports
+4
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unclassifiable adverse event changes

FDA AER · VeDDRA plate

Code 2190 VOL-MID

VOL-MID · DEATH-PAR · TOP-DECILE · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,876 reports
  • DEATH-PAR 8.1%
  • TOP-DECILE #164/2481
  • PHOTO-FINISH Vials, Leaking
  • SPECIES-HUMAN Human · 1,683
  • DRUG-LEAD Selamectin · 363
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Vials, Leaking (±11 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Unclassifiable adverse event

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Drug dose administrat… · near2892Skin scab · near2891Vials, Leaking · near2887Unclassifiable advers… · thi…2876Neurological signs NOS · near2859Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Unclassifiable adverse event

What the FDA AER plate says about Unclassifiable adverse event

Signature read: 2,876 reports place Unclassifiable adverse event in the upper third of FDA AER volume (#164 of 2,481). Report volume is upper-third scale: 2,876 named reports in the openFDA extract. 234 of 2,876 reports were death-coded (8.1% of named reports, not a population mortality rate). Nearest volume peer: Vials, Leaking (±11 reports). Lead species Human (1,683). Lead co-reported drug Selamectin (363).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Selamectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 1,683
Dog 753
Cat 226
Cattle 99
Unknown 63
Pig 21
Horse 14
Other 3
Sheep 3
Turkey 2

Breeds Most Affected

Unknown 1,774
Dog (unknown) 273
Cat (unknown) 112
Domestic Shorthair 53
Retriever - Labrador 44
Crossbred Canine/dog 38
Shepherd Dog - German 22
Cattle (other) 20
Mixed (Cattle) 20
Retriever - Golden 19

Associated Drugs

Selamectin 363
Ivermectin 111
Milbemycin Oxime + Spinosad 109
Spinosad 97
Mercaptobenzothiazole 97
Tilmicosin Phosphate 95
Tulathromycin 87
Buprenorphine 71
Milbemycin Oxime + Praziquantel 71
Imidacloprid, Moxidectin 66
Meloxicam 61
Moxidectin 57
Ceftiofur 52
Monensin Sodium 51
Fluralaner Chew Tablets 51
Enrofloxacin 49
Carprofen 49
Cyclosporin Ointment 48
Pyrantel Pamoate 46
Doramectin 44

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Unclassifiable adverse event, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (8.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unclassifiable adverse event (#164 of 2,481 by report volume); death-coded 8.1%. PlainBreed reaction plate · report volume stamp 2,876 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →