Reaction profile

The FDA adverse-event record for obstructive airway cough

29 FDA adverse-event reports reference obstructive airway cough (VeDDRA 883). See the species, breeds, and drugs most associated with it below.

29
reports citing this reaction
17.2%
death-coded share
Dog
most-affected species
Imidacloprid + Moxidectin
most-associated drug
Verify with FDA CVM →
29
Total Reports
5
Deaths
17.2%
Death Rate

Species Most Affected

Dog 23
Cat 3
Horse 2
Cattle 1

Breeds Most Affected

Shih Tzu 3
Domestic Shorthair 3
Retriever - Labrador 3
Sheepdog - Shetland 2
Bichon Frise 2
Pit Bull 2
Collie (unspecified) 1
Pointer (unspecified) 1
Terrier - Yorkshire 1
Dog (unknown) 1

Associated Drugs

Imidacloprid + Moxidectin 5
Milbemycin Oxime + Spinosad 5
Maropitant Citrate 3
Enrofloxacin 2
Gabapentin 2
Trilostane 2
Spinosad 2
Pergolide Mesylate 2
Milbemycin Oxime + Praziquantel 2
Trimeprazine With Prednisolone 1
Diphenhydramine 1
Milbemycin Oxime + Lufenuron 1
Praziquantel 1
Ponazuril 1
Imidacloprid + Pyriproxyfen 1
Peniciilin G 1
Pyrantel Pamoate 1
Fenbendazole 1
Feline Viral Rhinotracheitis/Calcivirus/Panleukopenia 1
Isotonic Sterile Fluids 1

Obstructive airway cough Reaction Insights

29 reports name Obstructive airway cough; 5 recorded a death outcome (17.2% of reported events, not a population-level mortality rate). VeDDRA code: 883.

By species: Dog (23 reports), Cat (3 reports), Horse (2 reports). By breed: Shih Tzu (3), Domestic Shorthair (3), Retriever - Labrador (3).

Most co-reported drugs: Imidacloprid + Moxidectin (5 reports), Milbemycin Oxime + Spinosad (5 reports), Maropitant Citrate (3 reports), Enrofloxacin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.