Reaction profile

The FDA adverse-event record for hypoglycaemia

3,880 FDA adverse-event reports reference hypoglycaemia (VeDDRA 1947). See the species, breeds, and drugs most associated with it below.

3,880
reports citing this reaction
25.6%
death-coded share
Dog
most-affected species
Insulin Injectable Vial
most-associated drug
Verify with FDA CVM →
3,880
Total Reports
995
Deaths
25.6%
Death Rate

Species Most Affected

Dog 2,587
Cat 1,270
Horse 10
Ferret 5
Cattle 3
Other 2
Pig 1
Other Canids 1
Human 1

Breeds Most Affected

Domestic Shorthair 711
Crossbred Canine/dog 298
Retriever - Labrador 233
Terrier - Yorkshire 172
Chihuahua 166
Domestic (unspecified) 123
Cat (unknown) 119
Domestic Longhair 114
Shih Tzu 98
Maltese 79

Associated Drugs

Insulin Injectable Vial 844
Bexagliflozin 347
Maropitant Citrate 281
Carprofen 262
Trilostane 194
Protamine Zinc Recombinant Human Insulin 165
Recombinant Human Insulin 158
Milbemycin Oxime + Spinosad 154
Dextrose 121
Human Insulin 115
Insulin 106
Porcine Insulin 103
Afoxolaner 101
Velagliflozin Proline Monohydrate 98
Oclacitinib Maleate 93
Meloxicam 91
Gabapentin 91
Cefovecin 89
Moxidectin 87
Fluralaner Chew Tablets 76

Hypoglycaemia Reaction Insights

3,880 reports name Hypoglycaemia; 995 recorded a death outcome (25.6% of reported events, not a population-level mortality rate). VeDDRA code: 1947.

By species: Dog (2,587 reports), Cat (1,270 reports), Horse (10 reports). By breed: Domestic Shorthair (711), Crossbred Canine/dog (298), Retriever - Labrador (233).

Most co-reported drugs: Insulin Injectable Vial (844 reports), Bexagliflozin (347 reports), Maropitant Citrate (281 reports), Carprofen (262 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.