Reaction profile

The FDA adverse-event record for serum amyloid a high, blood

Name: SERUM AMYLOID A HIGH, BLOOD - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

15 FDA reports name serum amyloid a high, blood, a lower-volume reaction in the CVM extract (VeDDRA 93045). Plate stamps and neighbourhood peers follow.

#2314 of 2,481
by report volume (all reactions): 15
reports citing this reaction: 6.7%
death-coded share: Horse
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. SERUM AMYLOID A HIGH, BLOOD has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

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FDA AER · VeDDRA plate

Code 93045 VOL-TRACE

VOL-TRACE · DEATH-PAR · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 15 reports
DEATH-PAR 6.7%
BOTTOM-DECILE #2314/2481
PHOTO-FINISH Abomasal ulcer
SPECIES-HORSE Horse · 15
DRUG-LEAD Polysulfated Glyc… · 10
DESK-WIDE 8 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abomasal ulcer (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around SERUM AMYLOID A HIGH, BLOOD

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around SERUM AMYLOID A HIGH, BLOOD

SERUM AMYLOID A HIGH, BLOOD: low death-coded share in the FDA AER plate

Signature read: 15 reports place SERUM AMYLOID A HIGH, BLOOD in the lower third of FDA AER volume (#2314 of 2,481). Report volume is lower-third scale: 15 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 15 reports (6.7% of named reports). Nearest volume peer: Abomasal ulcer (±0 reports). Lead species Horse (15). Lead co-reported drug Polysulfated Glycosaminoglycan (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Polysulfated Glycosaminoglycan appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 15

Breeds Most Affected

Quarter Horse 5

Thoroughbred 4

Mule not Specified 1

Percheron 1

Warmblood - Dutch 1

Miniature 1

Horse (unknown) 1

Warmblood (unspecified) 1

Associated Drugs

Polysulfated Glycosaminoglycan 10

Flunixin 3

Hyaluronate Sodium 2

Firocoxib 2

Dexamethasone 2

Clodronate Disodium 1

Levothyroxine Sodium 1

Neomycin-Polymyxin B-Dexameth 1

Flax Seed, Flax Oil, Rice Bran, Digestive Care (Dried Aspergillus Oryzae Fermentation Product On Wheat Bran, Saccharomyces C. Boulardii And Saccharomyces Cerevisiae With Stearic Acid Microencapsulatio 1

Altrenogest 1

Ration Balancer 1

Pelleted Feed 1

Stabilized Rice Bran 1

Sugar, Sodium Chloride, Potassium Chloride, Potassium Citrate, Lecithin, Magnesium Sulfate, Calcium Citrate, Canola Oil, Polyoxyethylene Glycol (400) Mono And Dioleates, Sodium Aluminosilicate, Natura 1

Gentamicin 1

Pergolide Mesylate 1

Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus 1

Eastern Encephalomyelitis Virus, Killed Virus + Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus 1

Flunixin Meglumine 1

Dipyrone 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for SERUM AMYLOID A HIGH, BLOOD (#2314 of 2,481 by report volume); death-coded 6.7%. PlainBreed reaction plate · report volume stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →