Reaction profile

The FDA adverse-event record for serum amyloid a high, blood

Name: SERUM AMYLOID A HIGH, BLOOD - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

15 FDA adverse-event reports reference serum amyloid a high, blood (VeDDRA 93045). See the species, breeds, and drugs most associated with it below.

15
reports citing this reaction: 6.7%
death-coded share: Horse
most-affected species: Polysulfated Glycosaminoglycan
most-associated drug

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Total Reports

Deaths

6.7%

Death Rate

Species Most Affected

Horse 15

Breeds Most Affected

Quarter Horse 5

Thoroughbred 4

Mule not Specified 1

Percheron 1

Warmblood - Dutch 1

Miniature 1

Horse (unknown) 1

Warmblood (unspecified) 1

Associated Drugs

Polysulfated Glycosaminoglycan 10

Flunixin 3

Firocoxib 2

Hyaluronate Sodium 2

Dexamethasone 2

Clodronate Disodium 1

Levothyroxine Sodium 1

Neomycin-Polymyxin B-Dexameth 1

Flax Seed, Flax Oil, Rice Bran, Digestive Care (Dried Aspergillus Oryzae Fermentation Product On Wheat Bran, Saccharomyces C. Boulardii And Saccharomyces Cerevisiae With Stearic Acid Microencapsulatio 1

Altrenogest 1

Ration Balancer 1

Pelleted Feed 1

Stabilized Rice Bran 1

Sugar, Sodium Chloride, Potassium Chloride, Potassium Citrate, Lecithin, Magnesium Sulfate, Calcium Citrate, Canola Oil, Polyoxyethylene Glycol (400) Mono And Dioleates, Sodium Aluminosilicate, Natura 1

Gentamicin 1

Pergolide Mesylate 1

Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus 1

Eastern Encephalomyelitis Virus, Killed Virus + Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus 1

Flunixin Meglumine 1

Dipyrone 1

SERUM AMYLOID A HIGH, BLOOD Reaction Insights

15 reports name SERUM AMYLOID A HIGH, BLOOD; 1 recorded a death outcome (6.7% of reported events, not a population-level mortality rate). VeDDRA code: 93045.

By species: Horse (15 reports). By breed: Quarter Horse (5), Thoroughbred (4), Mule not Specified (1).

Most co-reported drugs: Polysulfated Glycosaminoglycan (10 reports), Flunixin (3 reports), Firocoxib (2 reports), Hyaluronate Sodium (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.