Reaction profile

The FDA adverse-event record for malodour

1,042 FDA adverse-event reports reference malodour (VeDDRA 908). See the species, breeds, and drugs most associated with it below.

1,042
reports citing this reaction
6.8%
death-coded share
Dog
most-affected species
Imidacloprid + Moxidectin
most-associated drug
Verify with FDA CVM →
1,042
Total Reports
71
Deaths
6.8%
Death Rate

Species Most Affected

Dog 931
Cat 84
Human 17
Cattle 5
Unknown 3
Horse 2

Breeds Most Affected

Retriever - Labrador 92
Crossbred Canine/dog 64
Retriever - Golden 51
Chihuahua 46
Shepherd Dog - German 46
Shih Tzu 45
Domestic Shorthair 45
Dog (unknown) 44
Pit Bull 39
Terrier - Yorkshire 34

Associated Drugs

Imidacloprid + Moxidectin 168
Tigilanol Tiglate 127
Milbemycin Oxime + Spinosad 111
Afoxolaner 82
Spinosad 74
Prednisone 45
Diphenhydramine 41
Carprofen 39
Oclacitinib Maleate 35
Famotidine 32
Gabapentin 32
Butorphanol 30
Ivermectin + Pyrantel As Pamoate Salt 29
Fluralaner Chew Tablets 29
Dexmedetomidine 27
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 26
Trilostane 24
Maropitant Citrate 24
Imidacloprid, Moxidectin 23
Selamectin 20

Malodour Reaction Insights

1,042 reports name Malodour; 71 recorded a death outcome (6.8% of reported events, not a population-level mortality rate). VeDDRA code: 908.

By species: Dog (931 reports), Cat (84 reports), Human (17 reports). By breed: Retriever - Labrador (92), Crossbred Canine/dog (64), Retriever - Golden (51).

Most co-reported drugs: Imidacloprid + Moxidectin (168 reports), Tigilanol Tiglate (127 reports), Milbemycin Oxime + Spinosad (111 reports), Afoxolaner (82 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.