Reaction profile

The FDA adverse-event record for coughing blood

74 FDA adverse-event reports reference coughing blood (VeDDRA 1259). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1545 of 2,481
by report volume (all reactions)
74
reports citing this reaction
35.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Coughing blood has 74 reports now versus 73 in that prior snapshot: 1 more (1.4%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Coughing blood changes

FDA AER · VeDDRA plate

Code 1259 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 74 reports
  • DEATH-HOT 35.1%
  • MID-PACK #1545/2481
  • PHOTO-FINISH Abnormal tail posture
  • SPECIES-DOG Dog · 71
  • DRUG-LEAD Melarsomine Dihyd… · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal tail posture (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Coughing blood

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abnormal tail posture · near74Allergic oedema · near74Bronchopulmonary infl… · near74Cervical ventroflexion · near74Coughing blood · this reacti…74Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Coughing blood

Coughing blood: high death-coded share in the FDA AER plate

Signature read: Coughing blood's 35.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 26 of 74 reports (35.1% of named reports). Nearest volume peer: Abnormal tail posture (±0 reports). Lead species Dog (71). Lead co-reported drug Melarsomine Dihydrochloride Injection (15).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 71
Cat 2
Turtle 1

Breeds Most Affected

Retriever - Labrador 7
Pit Bull 7
Crossbred Canine/dog 4
Shepherd Dog - Australian 3
Bulldog 3
Terrier - Bull - American Pit 3
Chihuahua 3
Terrier - Yorkshire 2
Siberian Husky 2
Deutsche Dogge, Great Dane 2

Associated Drugs

Melarsomine Dihydrochloride Injection 15
Melarsomine Dihydrochloride 11
Carprofen 7
Maropitant Citrate 7
Ivermectin + Pyrantel As Pamoate Salt 6
Milbemycin Oxime + Spinosad 5
Bedinvetmab 4
Ketamine 3
Atipamezole Hydrochloride 3
Furosemide 3
Prednisone 3
Spinosad 3
Afoxolaner 3
Metronidazole 3
Meloxicam 3
Fluralaner Chew Tablets 3
Doxycycline 3
Lufenuron + Milbemycin Oxime + Praziquantel 3
Lotilaner 3
Milbemycin Oxime + Praziquantel 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Coughing blood, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (74 here).

Similar death-coded share

Nearest other reactions by death-coded share (35.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Coughing blood (#1545 of 2,481 by report volume); death-coded 35.1%. PlainBreed reaction plate · death-coded share stamp 35.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →