Reaction profile

The FDA adverse-event record for leukocytosis nos

205 FDA adverse-event reports reference leukocytosis nos (VeDDRA 163). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1022 of 2,481
by report volume (all reactions)
205
reports citing this reaction
24.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Leukocytosis NOS has 205 reports now versus 56 in that prior snapshot: 149 more (266.1%).

Report change
+149
Death-coded reports
+36
Death-coded share
−1.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Leukocytosis NOS changes

FDA AER · VeDDRA plate

Code 163 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 205 reports
  • DEATH-HOT 24.9%
  • MID-PACK #1022/2481
  • PHOTO-FINISH Heart valve disorder
  • SPECIES-DOG Dog · 147
  • DRUG-LEAD Maropitant Citrate · 48
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Heart valve disorder (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Leukocytosis NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Gum disorder NOS · near206Heart valve disorder · near205Hypermetria · near205Leukocytosis NOS · this reac…205Palpebral disorder NOS · near205Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Leukocytosis NOS

Leukocytosis NOS: high death-coded share in the FDA AER plate

Signature read: 51 death-coded reports is a heavy tail count for Leukocytosis NOS in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 51 of 205 reports (24.9% of named reports). Nearest volume peer: Heart valve disorder (±0 reports). Lead species Dog (147). Lead co-reported drug Maropitant Citrate (48).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 147
Cat 55
Horse 2
Goat 1

Breeds Most Affected

Domestic Shorthair 37
Retriever - Labrador 13
Chihuahua 10
Crossbred Canine/dog 9
Shepherd Dog - German 7
Shepherd Dog - Australian 6
Retriever - Golden 5
Poodle - Standard 5
Bulldog - French 5
Terrier - Bull - American Pit 5

Associated Drugs

Maropitant Citrate 48
Bedinvetmab 34
Gabapentin 27
Carprofen 23
Rabies Vaccine 14
Doxycycline 14
Velagliflozin Proline Monohydrate 14
Fluid Therapy 13
Moxidectin 12
Capromorelin 12
Prednisone 12
Butorphanol 11
Oclacitinib Maleate 11
Frunevetmab 11
Cefovecin 11
Buprenorphine 10
Trilostane 9
Diphenhydramine 9
Anti-Il31 Mab Mcs Lot #1283563 9
Grapiprant 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Leukocytosis NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (205 here).

Similar death-coded share

Nearest other reactions by death-coded share (24.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Leukocytosis NOS (#1022 of 2,481 by report volume); death-coded 24.9%. PlainBreed reaction plate · death-coded report count stamp 51 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →