Trigeminus paralysis

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VeDDRA Code: 1149

15 adverse event reports referencing this reaction

15
Total Reports
3
Deaths
2000.0%
Death Rate

Species Most Affected

Dog 14
Cat 1

Breeds Most Affected

Retriever - Golden 2
Terrier - Bull - American Pit 2
Mixed (Dog) 1
Retriever - Labrador 1
Lhasa Apso 1
Terrier (unspecified) 1
Spaniel (unspecified) 1
Dog (unknown) 1
Poodle (unspecified) 1
Dachshund - Miniature 1

Associated Drugs

Fluralaner Chew Tablets 2
Oclacitinib Maleate 2
Sarolaner 2
Prednisone 2
Bedinvetmab 2
Cefpodoxime Proxetil 1
Spinosad 1
Maropitant Citrate 1
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 1
Ivermectin 68Mcg Pyrantel 57Mg 1
Insulin Injectable Vial 1
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1
Anti-Il31 Mab Mcs Lot #1283563 1
Milbemycin Oxime & Lufenuron 1
Cefpodoxime 1
Doxycycline 1
Ivermectin/Pyrantel 1
Rabies Virus, 1
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 1
Melarsomine Dihydrochloride 1

Data Summary

Metric Value
Total reports referencing reaction 15
Reports with fatal outcome 3
Case-fatality rate (reported events) 2000.0%
Species observed 2
Breeds observed 13
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1149.

Trigeminus paralysis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 15 adverse event reports that reference Trigeminus paralysis as a reaction term, including 3 reports with a death outcome — a 2000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1149, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Trigeminus paralysis appears most frequently in reports for Dog (14 reports), Cat (1 reports) — with Dog dominating at 14 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Golden (2), Terrier - Bull - American Pit (2), Mixed (Dog) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Trigeminus paralysis are Fluralaner Chew Tablets (2 reports), Oclacitinib Maleate (2 reports), Sarolaner (2 reports), Prednisone (2 reports), with Fluralaner Chew Tablets appearing alongside this reaction in 2 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial