Reaction profile

The FDA adverse-event record for trigeminus paralysis

15 FDA adverse-event reports reference trigeminus paralysis (VeDDRA 1149). See the species, breeds, and drugs most associated with it below.

15
reports citing this reaction
20.0%
death-coded share
Dog
most-affected species
Fluralaner Chew Tablets
most-associated drug
Verify with FDA CVM →
15
Total Reports
3
Deaths
20.0%
Death Rate

Species Most Affected

Dog 14
Cat 1

Breeds Most Affected

Retriever - Golden 2
Terrier - Bull - American Pit 2
Mixed (Dog) 1
Retriever - Labrador 1
Lhasa Apso 1
Terrier (unspecified) 1
Spaniel (unspecified) 1
Dog (unknown) 1
Poodle (unspecified) 1
Dachshund - Miniature 1

Associated Drugs

Fluralaner Chew Tablets 2
Oclacitinib Maleate 2
Sarolaner 2
Prednisone 2
Bedinvetmab 2
Cefpodoxime Proxetil 1
Spinosad 1
Maropitant Citrate 1
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 1
Ivermectin 68Mcg Pyrantel 57Mg 1
Insulin Injectable Vial 1
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1
Anti-Il31 Mab Mcs Lot #1283563 1
Milbemycin Oxime & Lufenuron 1
Cefpodoxime 1
Doxycycline 1
Ivermectin/Pyrantel 1
Rabies Virus, 1
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 1
Melarsomine Dihydrochloride 1

Trigeminus paralysis Reaction Insights

15 reports name Trigeminus paralysis; 3 recorded a death outcome (20.0% of reported events, not a population-level mortality rate). VeDDRA code: 1149.

By species: Dog (14 reports), Cat (1 reports). By breed: Retriever - Golden (2), Terrier - Bull - American Pit (2), Mixed (Dog) (1).

Most co-reported drugs: Fluralaner Chew Tablets (2 reports), Oclacitinib Maleate (2 reports), Sarolaner (2 reports), Prednisone (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.