Is your pet's medication
actually safe?
According to FDA CVM openFDA filings as of July 2026 extract, PlainBreed indexes 1,085,823 animal adverse-event reports across 510 breeds and 2,679 drugs. Search the federal record.
- Adverse-event reports
- 1,085,823
- Breeds tracked
- 510
- Drugs referenced
- 2,679
- Reaction types
- 2,514
For information only. Adverse-event reports do not establish that a product caused or contributed to an event. Always consult your veterinarian.
- 1. Vomiting 174,348
- 2. Lethargy (see also Central nervous system depression in 'Neurological') 92,802
- 3. Emesis 69,317
- 4. Diarrhoea 64,292
- 5. Lack of efficacy (ectoparasite) - flea 59,231
- 6. Lack of efficacy - NOS 54,525
- 7. Lack of efficacy (endoparasite) - heartworm 52,770
The FDA record at a glance
According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).
- 93,675
- Retriever - Labrador reports (#1)
- 99.0%
- Atlantic Salmon (Salmo salar) death share (#1)
- #195
- Retriever - Labrador death-share rank
- #233
- Atlantic Salmon (Salmo salar) report rank
Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.
Breed inventory by species family
Exclusive partition of the 510 breed rows PlainBreed indexes. Parts sum to the breed total (Livestock = cattle, pig, goat, sheep, chicken, turkey).
By Species
View all species →Top Dog Breeds
All dog breeds →Top Cat Breeds
All cat breeds →Top Horse Breeds
All horse breeds →Most Reported Reactions
View all 2,514 reaction types →FDA animal adverse-event reports by year
FDA CVM Animal Adverse Event database, total reports filed per year
Report volume vs. death rate, by breed
Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.
Frequently Asked Questions
What is PlainBreed?
PlainBreed provides searchable FDA animal adverse event data covering 510 breeds, 2,679 drugs, and 1,085,823 reports to help pet owners research medication safety.
How can I look up my pet medication?
Search by drug name, breed, or reaction type to find adverse event reports. Each report includes the animal species, drug involved, and reported outcome.
Where does PlainBreed data come from?
All data comes from the FDA openFDA Animal & Veterinary Adverse Event database, which collects voluntary reports from veterinarians and pet owners.
Pet Medication Safety Guides
Understanding Adverse Event Reports
What FDA reports are, how they're collected, and what they mean for pet owners.
Pet Medication Safety, Using FDA Data
How to evaluate medication risks, common reactions by category, and how to report side effects.
Breed-Specific Adverse Event Risks
Why breed matters, how size and genetics affect drug sensitivity, and how to read PlainBreed data.
Most Commonly Reported Pet Medications
Which drugs top the FDA adverse event list, documented reactions, and how to read report volumes in context.
How FDA CVM Tracks Animal Adverse Events
The reporting process, mandatory vs. voluntary submissions, database limitations, and what trends reveal.
Related Guides
Editorial context for the plainbreed dataset, methodology, comparisons, and deep dives into the underlying records.
Research
Original analysis from PlainBreed, every statistic derived from our own database. See all research.
Breed Weight and Death-Coded Report Share in Dogs
Among well-reported dog breeds, larger breeds carry a higher share of death-coded FDA CVM reports, with the confounders spelled out.
ResearchAnimal Adverse-Event Report Trends, 2010–2026
How yearly FDA CVM report and death counts changed over time, and how large the dog share of each year really is.
Release change reportWhat Changed in the Latest FDA Data
A reproducible comparison with the prior 2025-Q4 source snapshot, including the largest added breed report counts.
What to do with this
510 breeds, 2,679 drugs, 1,085,823 FDA CVM reports, here's where to start.
- Look up how a specific breed reports compared to others. Browse breeds
- Check which reactions are most reported for a specific drug. Browse drugs
- See which adverse reactions are reported most often overall. Browse reactions
A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.
About this data
How PlainBreed works, and why you can trust these numbers
What this site is
PlainBreed is a plain-language reference for FDA veterinary adverse event data. We aggregate every report the FDA Center for Veterinary Medicine (CVM) publishes, voluntarily submitted by veterinarians, pet owners, and manufacturers, into a single searchable database covering 510 breeds, 2,679 drugs, and 1,085,823 reports, with every figure traceable back to the official FDA record.
Editorial process
- Source. Download the raw animal drug adverse event reports directly from the FDA Center for Veterinary Medicine (CVM) database.
- Verify. Normalize breed names, species, drug names, and reaction classifications so records aggregate consistently, then cross-check totals against the source file before they ever reach a page.
- Publish. Build breed, drug, and reaction profiles from the normalized data, always noting that a report does not prove a drug caused the reaction and that popular breeds simply generate more reports.
Editorial independence & corrections
PlainBreed is independent and accepts no payment, sponsorship, or promoted placement from any drug manufacturer or agency. Found an error or a stale record? File a correction via the contact page, we respond within 72 hours and reflect material corrections the next time the affected pages rebuild. See our methodology for full source attribution and processing detail.
Frequently asked
What is PlainBreed?
PlainBreed provides searchable FDA animal adverse event data covering 510 breeds, 2,679 drugs, and 1,085,823 reports to help pet owners research medication safety.
How can I look up my pet medication?
Search by drug name, breed, or reaction type to find adverse event reports. Each report includes the animal species, drug involved, and reported outcome.
Where does PlainBreed data come from?
All data comes from the FDA openFDA Animal & Veterinary Adverse Event database, which collects voluntary reports from veterinarians and pet owners.