Reaction profile

The FDA adverse-event record for tumbling circling disease (see also ataxia at 'neurological')

19 FDA reports name tumbling circling disease (see also ataxia at 'neurological'), a lower-volume reaction in the CVM extract (VeDDRA 370). Plate stamps and neighbourhood peers follow.

#2198 of 2,481
by report volume (all reactions)
19
reports citing this reaction
10.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tumbling circling disease (see also ataxia at 'Neurological') has 19 reports now versus 19 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tumbling circling disease (see also ataxia at 'Neurological') changes

FDA AER · VeDDRA plate

Code 370 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 19 reports
  • DEATH-ELEV 10.5%
  • LOWER-Q #2198/2481
  • PHOTO-FINISH Adaptor, damaged
  • SPECIES-DOG Dog · 14
  • DRUG-LEAD Milbemycin Oxime… · 3
  • DESK-WIDE 14 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, damaged (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Tumbling circling disease

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Adaptor, damaged · near19Amaurosis (see also P… · near19Anhidrosis · near19Cholelithiasis · near19Tumbling circling dis… · thi…19Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Tumbling circling disease (see also ataxia at 'Neurological')

What the FDA AER plate says about Tumbling circling disease (see also ataxia at 'Neurological')

Signature read: 19 reports place Tumbling circling disease (see also ataxia at 'Neurological') in the lower third of FDA AER volume (#2198 of 2,481). Report volume is lower-third scale: 19 named reports in the openFDA extract. 2 of 19 reports were death-coded (10.5% of named reports, not a population mortality rate). Nearest volume peer: Adaptor, damaged (±0 reports). Lead species Dog (14). Lead co-reported drug Milbemycin Oxime + Spinosad (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14
Cat 4
Horse 1

Breeds Most Affected

Chihuahua 3
Terrier - Yorkshire 2
Crossbred Canine/dog 2
Domestic Shorthair 2
Bichon Frise 1
Terrier (unspecified) 1
Dachshund - Miniature 1
Horse (unknown) 1
Pit Bull 1
Burmese 1

Associated Drugs

Milbemycin Oxime + Spinosad 3
Ivermectin + Pyrantel As Pamoate Salt 3
Afoxolaner 2
Selamectin 2
Betamethasone + Florfenicol + Terbinafine 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Maropitant Citrate 2
Cyclosporine A 1
Minocycline 1
Vinegar, Water, Hydrogen Peroxide Ear Wash 1
Sevoflurane 1
Methylprednisolone 1
Betamethasone Spray 1
Varied Supplements And Homeopathic Remedies 1
Doxycycline 1
Chloramphenicol 1
Linezolid 1
Pentoxyfilline 1
Niacinamide 1
Desoxycorticosterone Pivalate 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tumbling circling disease (see also ataxia at 'Neurological') (#2198 of 2,481 by report volume); death-coded 10.5%. PlainBreed reaction plate · report volume stamp 19 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →