Reaction profile

The FDA adverse-event record for pr-kidney(s), lesion(s)

449 FDA reports name pr-kidney(s), lesion(s), a high-volume reaction in the CVM extract (VeDDRA 99627). Plate stamps and neighbourhood peers follow.

#683 of 2,481
by report volume (all reactions)
449
reports citing this reaction
96.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-KIDNEY(S), LESION(S) has 449 reports now versus 449 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-KIDNEY(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99627 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 449 reports
  • DEATH-HOT 96.9%
  • MID-PACK #683/2481
  • PHOTO-FINISH Loss of bowel control
  • SPECIES-DOG Dog · 285
  • DRUG-LEAD Carprofen · 65
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Loss of bowel control (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around PR-KIDNEY, LESION

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Loss of bowel control · near449PR-KIDNEY(S), LESION(… · thi…449Temporary blindness · near449Application site grea… · near448Arched back · near448Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-KIDNEY(S), LESION(S)

PR-KIDNEY(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-KIDNEY(S), LESION(S)'s 96.9% death-coded share is among the highest in the openFDA reaction corpus. Report volume is upper-third scale: 449 named reports in the openFDA extract. Death-coded share is upper-third: 435 of 449 reports (96.9% of named reports). Nearest volume peer: Loss of bowel control (±0 reports). Lead species Dog (285). Lead co-reported drug Carprofen (65).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 285
Cat 130
Cattle 25
Horse 5
Other Birds 2
Turtle 1
Mouse 1

Breeds Most Affected

Domestic (unspecified) 64
Retriever - Labrador 44
Domestic Shorthair 36
Crossbred Canine/dog 29
Retriever - Golden 16
Holstein-Friesian also known as Holstein 13
Boxer (German Boxer) 10
Shepherd Dog - German 9
Chihuahua 9
Cat (unknown) 8

Associated Drugs

Carprofen 65
Robenacoxib 31
Milbemycin Oxime + Spinosad 29
Meloxicam 26
Cefovecin 23
Maropitant Citrate 23
Cefovecin Sodium 22
Fluralaner Chew Tablets 22
Spinosad 21
Moxidectin 21
Oclacitinib Maleate 18
Afoxolaner 18
Maropitant 17
Deracoxib 14
Dexmedetomidine Hydrochloride 14
Enrofloxacin 13
Grapiprant 12
Dexamethasone 9
Buprenorphine 9
Famotidine 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for PR-KIDNEY(S), LESION(S), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (449 here).

Similar death-coded share

Nearest other reactions by death-coded share (96.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-KIDNEY(S), LESION(S) (#683 of 2,481 by report volume); death-coded 96.9%. PlainBreed reaction plate · death-coded share stamp 96.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →