Reaction profile

The FDA adverse-event record for smelly breath

220 FDA adverse-event reports reference smelly breath (VeDDRA 1779). See the species, breeds, and drugs most associated with it below.

220
reports citing this reaction
22.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
220
Total Reports
49
Deaths
22.3%
Death Rate

Species Most Affected

Dog 181
Cat 37
Horse 2

Breeds Most Affected

Domestic Shorthair 28
Retriever - Labrador 18
Crossbred Canine/dog 14
Retriever - Golden 10
Terrier - Yorkshire 10
Shepherd Dog - German 10
Terrier - Boston 7
Chihuahua 7
Maltese 6
Beagle 5

Associated Drugs

Milbemycin Oxime + Spinosad 42
Imidacloprid + Moxidectin 24
Carprofen 17
Unspecified 17
Fluralaner Chew Tablets 14
Cyclosporine 13
Meloxicam 12
Maropitant Citrate 11
Spinosad 10
Oclacitinib Maleate 10
Cefovecin 9
Pyrantel Pamoate;Sarolaner 9
Afoxolaner 8
Buprenorphine 8
Bedinvetmab 7
Gabapentin 6
Robenacoxib 5
Polysulfated Glycosaminoglycan 5
Moxidectin 5
Milbemycin Oxime + Praziquantel 5

Smelly breath Reaction Insights

220 reports name Smelly breath; 49 recorded a death outcome (22.3% of reported events, not a population-level mortality rate). VeDDRA code: 1779.

By species: Dog (181 reports), Cat (37 reports), Horse (2 reports). By breed: Domestic Shorthair (28), Retriever - Labrador (18), Crossbred Canine/dog (14).

Most co-reported drugs: Milbemycin Oxime + Spinosad (42 reports), Imidacloprid + Moxidectin (24 reports), Carprofen (17 reports), Unspecified (17 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.