Polyarthropathy

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VeDDRA Code: 1118

23 adverse event reports referencing this reaction

23
Total Reports
5
Deaths
2170.0%
Death Rate

Species Most Affected

Dog 19
Cat 4

Breeds Most Affected

Domestic Shorthair 4
Retriever - Labrador 3
Crossbred Canine/dog 3
Boxer (German Boxer) 2
Shepherd Dog - Australian 2
Shepherd Dog - German 2
Spitz - Dutch (Keeshond) 1
Deutsche Dogge, Great Dane 1
Mixed (Dog) 1
Shih Tzu 1

Associated Drugs

Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str 3
Carprofen 3
Maropitant Citrate 3
Fluralaner Chew Tablets 3
Doxycycline 2
Moxidectin 2
Bordetella Bronchiseptica, Strain 78-9159, Kb 2
Oclacitinib Maleate 2
Da2Ppv+L*4 (Orig S-P Us) Lv+Kb 2
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 2
Ivermectin 1% Injection 1
Imidacloprid + Moxidectin 1
Prednisone 1
Azothiaprine 1
Milbemycin Oxime + Spinosad 1
Glucosamine + Chondroitin 1
Meloxicam 1
Ketamine Hydrochloride 1
Atipamezole Hydrochloride 1
Butorphanol Tartrate 1

Data Summary

Metric Value
Total reports referencing reaction 23
Reports with fatal outcome 5
Case-fatality rate (reported events) 2170.0%
Species observed 2
Breeds observed 13
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1118.

Polyarthropathy Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 23 adverse event reports that reference Polyarthropathy as a reaction term, including 5 reports with a death outcome — a 2170.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1118, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Polyarthropathy appears most frequently in reports for Dog (19 reports), Cat (4 reports) — with Dog dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (4), Retriever - Labrador (3), Crossbred Canine/dog (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Polyarthropathy are Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str (3 reports), Carprofen (3 reports), Maropitant Citrate (3 reports), Fluralaner Chew Tablets (3 reports), with Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial