Reaction profile

The FDA adverse-event record for polyarthropathy

23 FDA adverse-event reports reference polyarthropathy (VeDDRA 1118). See the species, breeds, and drugs most associated with it below.

23
reports citing this reaction
21.7%
death-coded share
Dog
most-affected species
Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str
most-associated drug
Verify with FDA CVM →
23
Total Reports
5
Deaths
21.7%
Death Rate

Species Most Affected

Dog 19
Cat 4

Breeds Most Affected

Domestic Shorthair 4
Retriever - Labrador 3
Crossbred Canine/dog 3
Boxer (German Boxer) 2
Shepherd Dog - Australian 2
Shepherd Dog - German 2
Spitz - Dutch (Keeshond) 1
Deutsche Dogge, Great Dane 1
Mixed (Dog) 1
Shih Tzu 1

Associated Drugs

Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str 3
Carprofen 3
Maropitant Citrate 3
Fluralaner Chew Tablets 3
Doxycycline 2
Moxidectin 2
Bordetella Bronchiseptica, Strain 78-9159, Kb 2
Oclacitinib Maleate 2
Da2Ppv+L*4 (Orig S-P Us) Lv+Kb 2
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 2
Ivermectin 1% Injection 1
Imidacloprid + Moxidectin 1
Prednisone 1
Azothiaprine 1
Milbemycin Oxime + Spinosad 1
Glucosamine + Chondroitin 1
Meloxicam 1
Ketamine Hydrochloride 1
Atipamezole Hydrochloride 1
Butorphanol Tartrate 1

Polyarthropathy Reaction Insights

23 reports name Polyarthropathy; 5 recorded a death outcome (21.7% of reported events, not a population-level mortality rate). VeDDRA code: 1118.

By species: Dog (19 reports), Cat (4 reports). By breed: Domestic Shorthair (4), Retriever - Labrador (3), Crossbred Canine/dog (3).

Most co-reported drugs: Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str (3 reports), Carprofen (3 reports), Maropitant Citrate (3 reports), Fluralaner Chew Tablets (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.