Reaction profile

The FDA adverse-event record for ataxia

21,626 FDA reports name ataxia, a high-volume reaction in the CVM extract (VeDDRA 654). Plate stamps and neighbourhood peers follow.

#16 of 2,481
by report volume (all reactions)
21,626
reports citing this reaction
13.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ataxia has 21,626 reports now versus 21,339 in that prior snapshot: 287 more (1.3%).

Report change
+287
Death-coded reports
+36
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ataxia changes

FDA AER · VeDDRA plate

Code 654 VOL-HIGH

VOL-HIGH · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 21,626 reports
  • DEATH-ELEV 13.0%
  • TOP-DECILE #16/2481
  • PHOTO-FINISH Other abnormal test r…
  • SPECIES-DOG Dog · 16,453
  • DRUG-LEAD Milbemycin Oxime… · 2,734
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Other abnormal test result NOS (±464 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Ataxia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Digestive tract disor… · near22748Ataxia · this reaction21626Other abnormal test r… · near21162Death by euthanasia · near21034Not eating · near21007Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Ataxia

What the FDA AER plate says about Ataxia

Signature read: 2,812 death-coded reports is a heavy tail count for Ataxia in the CVM extract. Report volume is upper-third scale: 21,626 named reports in the openFDA extract. 2,812 of 21,626 reports were death-coded (13.0% of named reports, not a population mortality rate). Nearest volume peer: Other abnormal test result NOS (±464 reports). Lead species Dog (16,453). Lead co-reported drug Milbemycin Oxime + Spinosad (2,734).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 16,453
Cat 4,592
Horse 321
Cattle 113
Pig 23
Goat 15
Human 14
Sheep 12
Turkey 10
Chicken 9

Breeds Most Affected

Domestic Shorthair 2,556
Retriever - Labrador 1,534
Crossbred Canine/dog 1,334
Chihuahua 900
Retriever - Golden 731
Terrier - Yorkshire 720
Shepherd Dog - German 600
Shih Tzu 491
Boxer (German Boxer) 472
Dog (unknown) 469

Associated Drugs

Milbemycin Oxime + Spinosad 2,734
Bedinvetmab 1,585
Spinosad 1,200
Carprofen 1,094
Sarolaner 1,028
Afoxolaner 1,008
Pyrantel Pamoate;Sarolaner 982
Maropitant Citrate 830
Imidacloprid + Moxidectin 772
Selamectin 686
Ivermectin 677
Moxidectin 655
Gabapentin 623
Cefovecin 524
Ivermectin + Pyrantel As Pamoate Salt 494
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 494
Milbemycin Oxime + Praziquantel 490
Fluralaner Chew Tablets 444
Fluralaner 13.64% 12-Week Chew 401
Emodepside + Praziquantel 390

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Ataxia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (13.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ataxia (#16 of 2,481 by report volume); death-coded 13.0%. PlainBreed reaction plate · death-coded report count stamp 2,812 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →