Reaction profile

The FDA adverse-event record for decreased pulse oxygenation

191 FDA adverse-event reports reference decreased pulse oxygenation (VeDDRA 2486). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1062 of 2,481
by report volume (all reactions)
191
reports citing this reaction
49.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased pulse oxygenation has 191 reports now versus 183 in that prior snapshot: 8 more (4.4%).

Report change
+8
Death-coded reports
+4
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased pulse oxygenation changes

FDA AER · VeDDRA plate

Code 2486 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 191 reports
  • DEATH-HOT 49.7%
  • MID-PACK #1062/2481
  • PHOTO-FINISH Bloody stool
  • SPECIES-DOG Dog · 154
  • DRUG-LEAD Isoflurane · 35
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bloody stool (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Decreased pulse oxygenation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bloody stool · near191Decreased pulse oxyge… · thi…191Dizziness · near191Enlarged kidney(s) · near191Gingival disorder · near191Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased pulse oxygenation

Decreased pulse oxygenation: high death-coded share in the FDA AER plate

Signature read: Decreased pulse oxygenation's 49.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 95 of 191 reports (49.7% of named reports). Nearest volume peer: Bloody stool (±0 reports). Lead species Dog (154). Lead co-reported drug Isoflurane (35).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 154
Cat 32
Human 3
Other Mammals 1
Horse 1

Breeds Most Affected

Domestic Shorthair 16
Chihuahua 10
Retriever - Golden 9
Bulldog - French 9
Retriever - Labrador 9
Domestic Longhair 7
Shepherd Dog - Australian 7
Dog (unknown) 7
Crossbred Canine/dog 6
Dachshund (unspecified) 6

Associated Drugs

Isoflurane 35
Maropitant Citrate 25
Moxidectin 20
Carprofen 17
Propofol 16
Melarsomine Dihydrochloride 15
Dexmedetomidine Hydrochloride 14
Butorphanol 13
Enrofloxacin 12
Butorphanol Tartrate 11
Ketamine 11
Buprenorphine 11
Bedinvetmab 11
Doxycycline 10
Meloxicam 10
Furosemide 9
Prednisone 9
Oclacitinib Maleate 8
Dexamethasone 8
Gabapentin 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased pulse oxygenation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (191 here).

Similar death-coded share

Nearest other reactions by death-coded share (49.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased pulse oxygenation (#1062 of 2,481 by report volume); death-coded 49.7%. PlainBreed reaction plate · death-coded share stamp 49.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →