Hypersensitivity to movement

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VeDDRA Code: 707

74 adverse event reports referencing this reaction

74
Total Reports
5
Deaths
680.0%
Death Rate

Species Most Affected

Dog 66
Cat 5
Horse 2
Pig 1

Breeds Most Affected

Retriever - Labrador 7
Boxer (German Boxer) 6
Terrier - Yorkshire 6
Shih Tzu 6
Domestic Shorthair 5
Crossbred Canine/dog 4
Chihuahua 4
Retriever - Golden 3
Terrier - Scottish 2
Horse (unknown) 2

Associated Drugs

Milbemycin Oxime + Spinosad 24
Sarolaner 12
Cephalexin 5
Afoxolaner 5
Buprenorphine 4
Ivermectin + Pyrantel As Pamoate Salt 4
Spinosad 3
Imidacloprid + Moxidectin 3
Enrofloxacin 3
Famotidine 3
Pyrantel Pamoate;Sarolaner 3
Ivermectin 2
Fish Oil 2
Cefovecin 2
Acepromazine 2
Atipamezole Hydrochloride 2
Ketamine 2
Maropitant Citrate 2
Gabapentin 2
Butorphanol 2

Data Summary

Metric Value
Total reports referencing reaction 74
Reports with fatal outcome 5
Case-fatality rate (reported events) 680.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 707.

Hypersensitivity to movement Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 74 adverse event reports that reference Hypersensitivity to movement as a reaction term, including 5 reports with a death outcome — a 680.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 707, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hypersensitivity to movement appears most frequently in reports for Dog (66 reports), Cat (5 reports), Horse (2 reports) — with Dog dominating at 66 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (7), Boxer (German Boxer) (6), Terrier - Yorkshire (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hypersensitivity to movement are Milbemycin Oxime + Spinosad (24 reports), Sarolaner (12 reports), Cephalexin (5 reports), Afoxolaner (5 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 24 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial