Low weight gain

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VeDDRA Code: 1048

163 adverse event reports referencing this reaction

163
Total Reports
32
Deaths
1960.0%
Death Rate

Species Most Affected

Dog 66
Cattle 65
Cat 13
Pig 8
Chicken 6
Bison 1
Turkey 1
Rabbit 1
Sheep 1
Horse 1

Breeds Most Affected

Aberdeen Angus 14
Cattle (unknown) 13
Cattle (other) 13
Retriever - Labrador 9
Shepherd Dog - German 8
Holstein-Friesian also known as Holstein 7
Retriever - Golden 6
Domestic Shorthair 5
Crossbred Bovine/Cattle 5
Greyhound 5

Associated Drugs

Eprinomectin 5% Injection 24
Monensin Sodium 22
Milbemycin Oxime + Spinosad 19
Milbemycin Oxime + Praziquantel 14
Moxidectin 8
Merial La Polypropylene Syringe 8
Ractopamine Hydrochloride 6
Praziquantel 5
Narasin 5
Ivermectin + Pyrantel As Pamoate Salt 5
Afoxolaner 4
Estradiol 3
Trenbolone; Estradiol; Tylosin Tartrate 3
Febantel + Praziquantel + Pyrantel Pamoate 3
Shampoo 3
Ivermectin 3
Carprofen 3
Milbemycin Oxime 3
Trenbolone Acetate;Estradiol Benzoate 3
Tylosin Phosphate 2

Data Summary

Metric Value
Total reports referencing reaction 163
Reports with fatal outcome 32
Case-fatality rate (reported events) 1960.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1048.

Low weight gain Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 163 adverse event reports that reference Low weight gain as a reaction term, including 32 reports with a death outcome — a 1960.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1048, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Low weight gain appears most frequently in reports for Dog (66 reports), Cattle (65 reports), Cat (13 reports) — with Dog dominating at 66 entries. Within those species, the breeds most often named alongside this reaction are Aberdeen Angus (14), Cattle (unknown) (13), Cattle (other) (13). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Low weight gain are Eprinomectin 5% Injection (24 reports), Monensin Sodium (22 reports), Milbemycin Oxime + Spinosad (19 reports), Milbemycin Oxime + Praziquantel (14 reports), with Eprinomectin 5% Injection appearing alongside this reaction in 24 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial