Reaction profile

The FDA adverse-event record for low weight gain

163 FDA adverse-event reports reference low weight gain (VeDDRA 1048). See the species, breeds, and drugs most associated with it below.

163
reports citing this reaction
19.6%
death-coded share
Dog
most-affected species
Eprinomectin 5% Injection
most-associated drug
Verify with FDA CVM →
163
Total Reports
32
Deaths
19.6%
Death Rate

Species Most Affected

Dog 66
Cattle 65
Cat 13
Pig 8
Chicken 6
Bison 1
Turkey 1
Rabbit 1
Sheep 1
Horse 1

Breeds Most Affected

Aberdeen Angus 14
Cattle (unknown) 13
Cattle (other) 13
Retriever - Labrador 9
Shepherd Dog - German 8
Holstein-Friesian also known as Holstein 7
Retriever - Golden 6
Domestic Shorthair 5
Crossbred Bovine/Cattle 5
Greyhound 5

Associated Drugs

Eprinomectin 5% Injection 24
Monensin Sodium 22
Milbemycin Oxime + Spinosad 19
Milbemycin Oxime + Praziquantel 14
Moxidectin 8
Merial La Polypropylene Syringe 8
Ractopamine Hydrochloride 6
Praziquantel 5
Narasin 5
Ivermectin + Pyrantel As Pamoate Salt 5
Afoxolaner 4
Estradiol 3
Trenbolone; Estradiol; Tylosin Tartrate 3
Febantel + Praziquantel + Pyrantel Pamoate 3
Shampoo 3
Ivermectin 3
Carprofen 3
Milbemycin Oxime 3
Trenbolone Acetate;Estradiol Benzoate 3
Tylosin Phosphate 2

Low weight gain Reaction Insights

163 reports name Low weight gain; 32 recorded a death outcome (19.6% of reported events, not a population-level mortality rate). VeDDRA code: 1048.

By species: Dog (66 reports), Cattle (65 reports), Cat (13 reports). By breed: Aberdeen Angus (14), Cattle (unknown) (13), Cattle (other) (13).

Most co-reported drugs: Eprinomectin 5% Injection (24 reports), Monensin Sodium (22 reports), Milbemycin Oxime + Spinosad (19 reports), Milbemycin Oxime + Praziquantel (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.