Reaction profile

The FDA adverse-event record for containers, abnormal

2,277 FDA reports name containers, abnormal, a high-volume reaction in the CVM extract (VeDDRA 99004). Plate stamps and neighbourhood peers follow.

#203 of 2,481
by report volume (all reactions)
2,277
reports citing this reaction
0.0%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Containers, Abnormal has 2,277 reports now versus 2,257 in that prior snapshot: 20 more (0.9%).

Report change
+20
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Containers, Abnormal changes

FDA AER · VeDDRA plate

Code 99004 VOL-MID

VOL-MID · DEATH-RARE · TOP-DECILE · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,277 reports
  • DEATH-RARE 0.0%
  • TOP-DECILE #203/2481
  • PHOTO-FINISH Muscle tremor
  • SPECIES-UNKNOWN Unknown · 2,246
  • DRUG-LEAD Ivermectin + Pyra… · 182
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Muscle tremor (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Containers, Abnormal

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Muscle tremor · near2279Containers, Abnormal · this …2277Anaphylactoid reaction · near2272Confusion · near2259Stumbling gait · near2252Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Containers, Abnormal

Containers, Abnormal: low death-coded share in the FDA AER plate

Signature read: Containers, Abnormal's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 2,277 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 2,277 reports (0.0% of named reports). Nearest volume peer: Muscle tremor (±2 reports). Lead species Unknown (2,246). Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt (182).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 2,246
Dog 19
Human 7
Cat 4
Cattle 1

Breeds Most Affected

Unknown 2,253
Dog (unknown) 2
Domestic Shorthair 2
Terrier - Yorkshire 1
Collie - Border 1
Maltese 1
Retriever - Golden 1
Dachshund (unspecified) 1
Domestic Longhair 1
Cattle (other) 1

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 182
Meloxicam 163
Afoxolaner 152
Ivermectin, Pyrantel 142
Pyrantel Pamoate;Sarolaner 84
Mirtazapine 79
Tulathromycin 57
Moxidectin 52
Sarolaner 47
Trilostane 42
Afoxolaner 28.3 Mg Chewable Tablets 37
Ivermectin 32
Zeranol 32
Selamectin 29
Cyclosporine 24
Dexamethasone + Neomycin Sulfate + Thiabendazole 24
Firocoxib 22
Carprofen 22
Insulin Injectable Vial 22
Maropitant Citrate 21

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Containers, Abnormal, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,277 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Containers, Abnormal (#203 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →