Reaction profile

The FDA adverse-event record for appetite disorder nos

436 FDA adverse-event reports reference appetite disorder nos (VeDDRA 1323). See the species, breeds, and drugs most associated with it below.

436
reports citing this reaction
11.9%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
436
Total Reports
52
Deaths
11.9%
Death Rate

Species Most Affected

Dog 354
Cat 76
Horse 3
Turkey 1
Cattle 1
Human 1

Breeds Most Affected

Domestic Shorthair 38
Retriever - Labrador 36
Crossbred Canine/dog 34
Shih Tzu 22
Retriever - Golden 19
Maltese 13
Chihuahua 13
Dog (unknown) 12
Beagle 11
Cat (unknown) 10

Associated Drugs

Trilostane 59
Milbemycin Oxime + Spinosad 46
Insulin Injectable Vial 33
Afoxolaner 24
Maropitant Citrate 23
Ivermectin + Pyrantel As Pamoate Salt 20
Gabapentin 18
Moxidectin 16
Oclacitinib Maleate 16
Spinosad 14
Bedinvetmab 14
Buprenorphine 13
Prednisone 12
Carprofen 12
Fluralaner Chew Tablets 12
Cefovecin 11
Milbemycin Oxime + Praziquantel 11
Selamectin 10
Pimobendan 10
Mirtazapine 10

Appetite disorder NOS Reaction Insights

436 reports name Appetite disorder NOS; 52 recorded a death outcome (11.9% of reported events, not a population-level mortality rate). VeDDRA code: 1323.

By species: Dog (354 reports), Cat (76 reports), Horse (3 reports). By breed: Domestic Shorthair (38), Retriever - Labrador (36), Crossbred Canine/dog (34).

Most co-reported drugs: Trilostane (59 reports), Milbemycin Oxime + Spinosad (46 reports), Insulin Injectable Vial (33 reports), Afoxolaner (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.