Reaction profile

The FDA adverse-event record for ear pain

444 FDA adverse-event reports reference ear pain (VeDDRA 347). See the species, breeds, and drugs most associated with it below.

444
reports citing this reaction
2.9%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
444
Total Reports
13
Deaths
2.9%
Death Rate

Species Most Affected

Dog 396
Cat 44
Human 3
Horse 1

Breeds Most Affected

Retriever - Labrador 58
Domestic Shorthair 29
Crossbred Canine/dog 27
Retriever - Golden 25
Shih Tzu 18
Chihuahua 16
Shepherd Dog - German 15
Boxer (German Boxer) 12
Bulldog 11
Poodle (unspecified) 11

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 101
Betamethasone + Florfenicol + Terbinafine 75
Genta/Momet/Clotrim Ear Oint 32
Prednisone 28
Carprofen 26
Milbemycin Oxime + Spinosad 22
Oclacitinib Maleate 22
Ear Cleaner (Unknown) 20
Maropitant Citrate 20
Florfenicol + Mometasone Furoate + Terbinafine 20
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 18
Ear Cleaner 17
Orbiflox/Momet/Posaco Eardrops 14
Florfenicol, Terbinafine, Betamethasone Acetate 14
Enrofloxacin 12
Enrofloxacin + Silver Sulfadiazine 11
Miconazole + Polymyxin B + Prednisolone 11
Afoxolaner 10
Diphenhydramine 10
Meloxicam 10

Ear pain Reaction Insights

444 reports name Ear pain; 13 recorded a death outcome (2.9% of reported events, not a population-level mortality rate). VeDDRA code: 347.

By species: Dog (396 reports), Cat (44 reports), Human (3 reports). By breed: Retriever - Labrador (58), Domestic Shorthair (29), Crossbred Canine/dog (27).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (101 reports), Betamethasone + Florfenicol + Terbinafine (75 reports), Genta/Momet/Clotrim Ear Oint (32 reports), Prednisone (28 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.