Reaction profile

The FDA adverse-event record for coprophagia

184 FDA adverse-event reports reference coprophagia (VeDDRA 133). See the species, breeds, and drugs most associated with it below.

184
reports citing this reaction
2.2%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Praziquantel
most-associated drug
Verify with FDA CVM →
184
Total Reports
4
Deaths
2.2%
Death Rate

Species Most Affected

Dog 179
Cat 4
Horse 1

Breeds Most Affected

Retriever - Labrador 17
Crossbred Canine/dog 15
Retriever - Golden 10
Dog (unknown) 9
Shepherd Dog - German 7
Collie - Border 6
Chihuahua 5
Beagle 5
Shih Tzu 5
Terrier - Yorkshire 4

Associated Drugs

Milbemycin Oxime + Praziquantel 37
Ivermectin + Pyrantel As Pamoate Salt 29
Milbemycin Oxime + Spinosad 26
Trilostane 19
Afoxolaner 9
Milbemycin Oxime 8
Milbemycin Oxime, Lufenuron 7
Lotilaner 7
Prednisone 6
Oclacitinib Maleate 6
Fluralaner 13.64% 12-Week Chew 5
Spinosad 4
Milbemcyin Oxime, Lufenuron, Praziquantel 4
Pyrantel Pamoate;Sarolaner 4
Levothyroxine Sodium 3
Fluralaner Chew Tablets 3
Diphenhydramine 3
Fenbendazole 3
Prednisolone 3
Milbemycin Oxime, Praziquantel 3

Coprophagia Reaction Insights

184 reports name Coprophagia; 4 recorded a death outcome (2.2% of reported events, not a population-level mortality rate). VeDDRA code: 133.

By species: Dog (179 reports), Cat (4 reports), Horse (1 reports). By breed: Retriever - Labrador (17), Crossbred Canine/dog (15), Retriever - Golden (10).

Most co-reported drugs: Milbemycin Oxime + Praziquantel (37 reports), Ivermectin + Pyrantel As Pamoate Salt (29 reports), Milbemycin Oxime + Spinosad (26 reports), Trilostane (19 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.