Reaction profile

The FDA adverse-event record for cardiorespiratory arrest

253 FDA adverse-event reports reference cardiorespiratory arrest (VeDDRA 219). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#932 of 2,481
by report volume (all reactions)
253
reports citing this reaction
87.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cardiorespiratory arrest has 253 reports now versus 246 in that prior snapshot: 7 more (2.8%).

Report change
+7
Death-coded reports
+7
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cardiorespiratory arrest changes

FDA AER · VeDDRA plate

Code 219 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 253 reports
  • DEATH-HOT 87.7%
  • MID-PACK #932/2481
  • PHOTO-FINISH Congested mucous memb…
  • SPECIES-DOG Dog · 173
  • DRUG-LEAD Maropitant Citrate · 48
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Congested mucous membrane (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Cardiorespiratory arrest

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Constricted pupils · near254Drug label confusion · near254Hearing affected · near254Cardiorespiratory arr… · thi…253Congested mucous memb… · near252Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cardiorespiratory arrest

Cardiorespiratory arrest: high death-coded share in the FDA AER plate

Signature read: Cardiorespiratory arrest's 87.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 222 of 253 reports (87.7% of named reports). Nearest volume peer: Congested mucous membrane (±1 reports). Lead species Dog (173). Lead co-reported drug Maropitant Citrate (48).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 173
Cat 76
Guinea Pig 2
Jaguar 1
Horse 1

Breeds Most Affected

Domestic Shorthair 43
Shih Tzu 16
Retriever - Labrador 11
Shepherd Dog - German 10
Chihuahua 10
Domestic Mediumhair 8
Bulldog - French 8
Pug 7
Crossbred Canine/dog 7
Dog (unknown) 6

Associated Drugs

Maropitant Citrate 48
Isoflurane 36
Carprofen 35
Butorphanol 30
Dexmedetomidine Hydrochloride 27
Propofol 25
Buprenorphine 25
Ketamine 20
Atipamezole Hydrochloride 18
Alfaxalone 18
Cefovecin 17
Moxidectin 16
Ketamine Hydrochloride 15
Dexmedetomidine 14
Meloxicam 13
Acepromazine Maleate 12
Butorphanol Tartrate 12
Gabapentin 11
Atropine 10
Epinephrine 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cardiorespiratory arrest, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (253 here).

Similar death-coded share

Nearest other reactions by death-coded share (87.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cardiorespiratory arrest (#932 of 2,481 by report volume); death-coded 87.7%. PlainBreed reaction plate · death-coded share stamp 87.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →