Reaction profile

The FDA adverse-event record for injection site serosanguinous discharge

283 FDA adverse-event reports reference injection site serosanguinous discharge (VeDDRA 104). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#895 of 2,481
by report volume (all reactions)
283
reports citing this reaction
7.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site serosanguinous discharge has 283 reports now versus 278 in that prior snapshot: 5 more (1.8%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site serosanguinous discharge changes

FDA AER · VeDDRA plate

Code 104 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 283 reports
  • DEATH-PAR 7.8%
  • MID-PACK #895/2481
  • PHOTO-FINISH Cardiomyopathy
  • SPECIES-DOG Dog · 270
  • DRUG-LEAD Tigilanol Tiglate · 146
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cardiomyopathy (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Injection site serosanguinous discharge

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiomyopathy · near283Cognitive disorder NOS · near283Injection site serosa… · thi…283Lack of efficacy (fun… · near283Peeling skin · near283Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site serosanguinous discharge

Injection site serosanguinous discharge: low death-coded share in the FDA AER plate

Signature read: Injection site serosanguinous discharge's 7.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 22 of 283 reports (7.8% of named reports). Nearest volume peer: Cardiomyopathy (±0 reports). Lead species Dog (270). Lead co-reported drug Tigilanol Tiglate (146).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tigilanol Tiglate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 270
Horse 4
Cat 4
Cattle 3
Donkey 1
Goat 1

Breeds Most Affected

Retriever - Labrador 38
Pit Bull 29
Boxer (German Boxer) 22
Dog (unknown) 17
Beagle 12
Crossbred Canine/dog 11
Bulldog - French 9
Shepherd Dog - German 7
Chihuahua 7
Terrier - Bull - American Pit 6

Associated Drugs

Tigilanol Tiglate 146
Prednisone 37
Gabapentin 35
Famotidine 30
Diphenhydramine 28
Carprofen 25
Melarsomine Dihydrochloride 25
Maropitant Citrate 21
Butorphanol 21
Dexmedetomidine 20
Buprenorphine 17
Propofol 16
Butorphanol Tartrate 13
Moxidectin 12
Hydromorphone 12
Atipamezole 11
Melarsomine Dihydrochloride Injection 10
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 9
Bupivacaine Lipsome Injectable Suspension 9
Ketamine 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site serosanguinous discharge, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (283 here).

Similar death-coded share

Nearest other reactions by death-coded share (7.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site serosanguinous discharge (#895 of 2,481 by report volume); death-coded 7.8%. PlainBreed reaction plate · death-coded share stamp 7.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →