Reaction profile

The FDA adverse-event record for rapid pulse rate

72 FDA adverse-event reports reference rapid pulse rate (VeDDRA 1719). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1560 of 2,481
by report volume (all reactions)
72
reports citing this reaction
26.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Rapid pulse rate has 72 reports now versus 70 in that prior snapshot: 2 more (2.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Rapid pulse rate changes

FDA AER · VeDDRA plate

Code 1719 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 72 reports
  • DEATH-HOT 26.4%
  • MID-PACK #1560/2481
  • PHOTO-FINISH Ear flapping/twitching
  • SPECIES-DOG Dog · 57
  • DRUG-LEAD Milbemycin Oxime… · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Ear flapping/twitching (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Rapid pulse rate

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Ear flapping/twitching · near72Elevated BUN · near72Embolism · near72Fatty liver · near72Rapid pulse rate · this reac…72Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Rapid pulse rate

Rapid pulse rate: high death-coded share in the FDA AER plate

Signature read: Rapid pulse rate's 26.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 19 of 72 reports (26.4% of named reports). Nearest volume peer: Ear flapping/twitching (±0 reports). Lead species Dog (57). Lead co-reported drug Milbemycin Oxime + Spinosad (15).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 57
Cat 9
Human 3
Horse 3

Breeds Most Affected

Domestic Shorthair 6
Shih Tzu 5
Unknown 4
Shepherd Dog - German 4
Collie - Border 3
Retriever - Golden 3
Terrier - Yorkshire 3
Spitz - German Pomeranian 3
Boxer (German Boxer) 3
Crossbred Canine/dog 3

Associated Drugs

Milbemycin Oxime + Spinosad 15
Gabapentin 9
Maropitant Citrate 7
Bedinvetmab 6
Prednisone 5
Moxidectin 5
Lotilaner 5
Milbemycin Oxime + Praziquantel 5
Diphenhydramine 5
Carprofen 4
Oclacitinib Maleate 4
Tramadol 4
Vaccines (Unknown) 3
Rabies Vaccine, Killed Virus 3
Butorphanol 3
Pyrantel Pamoate;Sarolaner 3
Famotidine 3
Polysulfated Glycosaminoglycan 3
Spinosad 2
Sarolaner 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Rapid pulse rate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (72 here).

Similar death-coded share

Nearest other reactions by death-coded share (26.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Rapid pulse rate (#1560 of 2,481 by report volume); death-coded 26.4%. PlainBreed reaction plate · death-coded share stamp 26.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →