Rapid pulse rate

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VeDDRA Code: 1719

68 adverse event reports referencing this reaction

68
Total Reports
18
Deaths
2650.0%
Death Rate

Species Most Affected

Dog 54
Cat 8
Human 3
Horse 3

Breeds Most Affected

Domestic Shorthair 6
Shih Tzu 5
Unknown 4
Shepherd Dog - German 4
Collie - Border 3
Retriever - Golden 3
Terrier - Yorkshire 3
Spitz - German Pomeranian 3
Crossbred Canine/dog 3
Boxer (German Boxer) 2

Associated Drugs

Milbemycin Oxime + Spinosad 15
Bedinvetmab 6
Moxidectin 5
Milbemycin Oxime + Praziquantel 5
Gabapentin 5
Maropitant Citrate 4
Lotilaner 4
Tramadol 4
Carprofen 3
Vaccines (Unknown) 3
Rabies Vaccine, Killed Virus 3
Oclacitinib Maleate 3
Diphenhydramine 3
Pyrantel Pamoate;Sarolaner 3
Polysulfated Glycosaminoglycan 3
Prednisone 2
Spinosad 2
Sarolaner 2
Hydromorphone 2
Buprenorphine 2

Data Summary

Metric Value
Total reports referencing reaction 68
Reports with fatal outcome 18
Case-fatality rate (reported events) 2650.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1719.

Rapid pulse rate Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 68 adverse event reports that reference Rapid pulse rate as a reaction term, including 18 reports with a death outcome — a 2650.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1719, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Rapid pulse rate appears most frequently in reports for Dog (54 reports), Cat (8 reports), Human (3 reports) — with Dog dominating at 54 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (6), Shih Tzu (5), Unknown (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Rapid pulse rate are Milbemycin Oxime + Spinosad (15 reports), Bedinvetmab (6 reports), Moxidectin (5 reports), Milbemycin Oxime + Praziquantel (5 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 15 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial