Reaction profile

The FDA adverse-event record for pitting oedema

114 FDA adverse-event reports reference pitting oedema (VeDDRA 2887). See the species, breeds, and drugs most associated with it below.

114
reports citing this reaction
28.1%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
114
Total Reports
32
Deaths
28.1%
Death Rate

Species Most Affected

Dog 104
Horse 5
Cat 4
Ferret 1

Breeds Most Affected

Retriever - Labrador 25
Dog (unknown) 8
Bulldog - French 5
Shepherd Dog - German 5
Weimaraner 4
Pit Bull 4
Beagle 4
Boxer (German Boxer) 4
Crossbred Canine/dog 4
Retriever - Golden 3

Associated Drugs

Bedinvetmab 38
Tigilanol Tiglate 32
Carprofen 24
Gabapentin 23
Maropitant Citrate 14
Diphenhydramine 13
Prednisone 11
Propofol 9
Famotidine 9
Butorphanol 8
Dexmedetomidine 8
Buprenorphine 6
Moxidectin 6
Atipamezole 6
Hydromorphone 5
Polysulfated Glycosaminoglycan 5
Doxycycline 5
Tramadol 5
Dexmedetomidine Hydrochloride 4
Isoflurane 4

Pitting oedema Reaction Insights

114 reports name Pitting oedema; 32 recorded a death outcome (28.1% of reported events, not a population-level mortality rate). VeDDRA code: 2887.

By species: Dog (104 reports), Horse (5 reports), Cat (4 reports). By breed: Retriever - Labrador (25), Dog (unknown) (8), Bulldog - French (5).

Most co-reported drugs: Bedinvetmab (38 reports), Tigilanol Tiglate (32 reports), Carprofen (24 reports), Gabapentin (23 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.