Reaction profile

The FDA adverse-event record for pr-thymus, lesion(s)

34 FDA adverse-event reports reference pr-thymus, lesion(s) (VeDDRA 99687). See the species, breeds, and drugs most associated with it below.

34
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species
Florfenicol, Flunixin
most-associated drug
Verify with FDA CVM →
34
Total Reports
34
Deaths
100.0%
Death Rate

Species Most Affected

Dog 14
Cattle 11
Cat 9

Breeds Most Affected

Holstein-Friesian also known as Holstein 11
Retriever - Labrador 6
Domestic Shorthair 3
Crossbred Canine/dog 2
Cat (unknown) 2
Persian 1
Retriever - Golden 1
Domestic (unspecified) 1
Spaniel - Cocker American 1
Collie - Border 1

Associated Drugs

Florfenicol, Flunixin 8
Carprofen 3
Tildipirosin 3
Cefovecin 3
Cefovecin Sodium 2
Maropitant 2
Imidacloprid + Moxidectin 2
Milbemycin Oxime + Spinosad 2
Diazepam 2
Selamectin 1
Methylprednisolone Acetate 1
Dexmedetomidine Hydrochloride 1
Moxidectin 1
Vitamin B12 1
Meloxicam 1
Praziquantel + Pyrantel 1
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1
Ticarcillin Disodium, Clavulanate Potassium 1
Vaccines (Unknown) 1
Anesthetic 1

PR-THYMUS, LESION(S) Reaction Insights

34 reports name PR-THYMUS, LESION(S); 34 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 99687.

By species: Dog (14 reports), Cattle (11 reports), Cat (9 reports). By breed: Holstein-Friesian also known as Holstein (11), Retriever - Labrador (6), Domestic Shorthair (3).

Most co-reported drugs: Florfenicol, Flunixin (8 reports), Carprofen (3 reports), Tildipirosin (3 reports), Cefovecin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.