Reaction profile

The FDA adverse-event record for myoglobinuria

Name: Myoglobinuria - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

20 FDA reports name myoglobinuria, a lower-volume reaction in the CVM extract (VeDDRA 2056). Plate stamps and neighbourhood peers follow.

#2168 of 2,481
by report volume (all reactions): 20
reports citing this reaction: 40.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Myoglobinuria has 20 reports now versus 20 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Myoglobinuria changes

FDA AER · VeDDRA plate

Code 2056 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 20 reports
DEATH-HOT 40.0%
LOWER-Q #2168/2481
PHOTO-FINISH Agalactia
SPECIES-DOG Dog · 17
DRUG-LEAD Moxidectin · 4
DESK-WIDE 14 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Agalactia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Myoglobinuria

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Myoglobinuria

Myoglobinuria: high death-coded share in the FDA AER plate

Signature read: 20 reports place Myoglobinuria in the lower third of FDA AER volume (#2168 of 2,481). Report volume is lower-third scale: 20 named reports in the openFDA extract. Death-coded share is upper-third: 8 of 20 reports (40.0% of named reports). Nearest volume peer: Agalactia (±0 reports). Lead species Dog (17). Lead co-reported drug Moxidectin (4).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 17

Horse 2

Cat 1

Breeds Most Affected

Shepherd Dog - German 4

Chihuahua 3

Retriever - Labrador 2

Quarter Horse 1

Domestic Shorthair 1

Horse (unknown) 1

Schipperke 1

Boxer (German Boxer) 1

Schnauzer (unspecified) 1

Retriever - Golden 1

Associated Drugs

Moxidectin 4

Polysulfated Glycosaminoglycan 2

Afoxolaner 2

Carprofen 2

Doxycycline 2

Bedinvetmab 2

Gabapentin 2

Cefovecin Sodium 1

Cefovecin 1

Clenbuterol Hydrochloride 1

Firocoxib 57 Mg Chewable 1

Afoxolaner 68 Mg Chewable Tablets 1

Milbemcyin Oxime, Lufenuron, Praziquantel 1

Ibuprofen 1

Tramadol 1

Glucosamine/Chondroitin With Avocado/Soybean Unsaponifiables 1

Butorphanol Tartrate 1

Dexmedetomidine 1

Atipameole Hcl 1

Famotidine 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Myoglobinuria (#2168 of 2,481 by report volume); death-coded 40.0%. PlainBreed reaction plate · report volume stamp 20 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →