Increased drinking

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VeDDRA Code: 3130

275 adverse event reports referencing this reaction

275
Total Reports
67
Deaths
2440.0%
Death Rate

Species Most Affected

Dog 229
Cat 43
Horse 2
Goat 1

Breeds Most Affected

Retriever - Labrador 33
Domestic Shorthair 27
Dog (unknown) 18
Crossbred Canine/dog 16
Retriever - Golden 16
Shepherd Dog - German 13
Terrier (unspecified) 8
Chihuahua 8
Siberian Husky 7
Terrier - Bull - American Pit 6

Associated Drugs

Bedinvetmab 146
Gabapentin 33
Carprofen 23
Maropitant Citrate 20
Pyrantel Pamoate;Sarolaner 16
Prednisone 12
Afoxolaner 12
Diphenhydramine 11
Oclacitinib Maleate 11
Frunevetmab 11
Anti-Il31 Mab Mcs Lot #1283563 9
Meloxicam 9
Bexagliflozin 9
Grapiprant 9
Famotidine 8
Doxycycline 8
Fluralaner 13.64% 12-Week Chew 8
Tigilanol Tiglate 7
Prednisolone 7
Buprenorphine 7

Data Summary

Metric Value
Total reports referencing reaction 275
Reports with fatal outcome 67
Case-fatality rate (reported events) 2440.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 3130.

Increased drinking Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 275 adverse event reports that reference Increased drinking as a reaction term, including 67 reports with a death outcome — a 2440.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 3130, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Increased drinking appears most frequently in reports for Dog (229 reports), Cat (43 reports), Horse (2 reports) — with Dog dominating at 229 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (33), Domestic Shorthair (27), Dog (unknown) (18). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Increased drinking are Bedinvetmab (146 reports), Gabapentin (33 reports), Carprofen (23 reports), Maropitant Citrate (20 reports), with Bedinvetmab appearing alongside this reaction in 146 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial