Reaction profile

The FDA adverse-event record for unthrifty

142 FDA adverse-event reports reference unthrifty (VeDDRA 1933). See the species, breeds, and drugs most associated with it below.

142
reports citing this reaction
39.4%
death-coded share
Cattle
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
142
Total Reports
56
Deaths
39.4%
Death Rate

Species Most Affected

Cattle 75
Pig 18
Dog 17
Cat 10
Horse 6
Chicken 5
Goat 5
Sheep 2
Unknown 2
Bison 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 21
Cattle (other) 16
Cattle (unknown) 15
Aberdeen Angus 10
Crossbred Porcine/Pig 10
Chicken (unknown) 5
Unknown 4
Domestic Shorthair 4
Crossbred Bovine/Cattle 4
Pig (unknown) 4

Associated Drugs

Monensin Sodium 34
Eprinomectin 5% Injection 12
Narasin 12
Moxidectin 10
Tilmicosin 8
Amoxicillin 5
Eprinomectin 0.5% Pour-On 4
Ivermectin 4
Ivermectin(1%)/Clorsulon(10%) Injection 4
Merial La Polypropylene Syringe 4
Carbadox 4
Doramectin 3
Beta-Mannanase 3
Milbemycin Oxime + Spinosad 3
Enrofloxacin 3
Tulathromycin 3
Dried Yeast, L-Arginine, L-Leucine 3
Vegetable Oil 3
Imidacloprid + Moxidectin 2
Semduramicin 2

Unthrifty Reaction Insights

142 reports name Unthrifty; 56 recorded a death outcome (39.4% of reported events, not a population-level mortality rate). VeDDRA code: 1933.

By species: Cattle (75 reports), Pig (18 reports), Dog (17 reports). By breed: Holstein-Friesian also known as Holstein (21), Cattle (other) (16), Cattle (unknown) (15).

Most co-reported drugs: Monensin Sodium (34 reports), Eprinomectin 5% Injection (12 reports), Narasin (12 reports), Moxidectin (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.