Reaction profile

The FDA adverse-event record for enucleation

15 FDA reports name enucleation, a lower-volume reaction in the CVM extract (VeDDRA 93098). Plate stamps and neighbourhood peers follow.

#2298 of 2,481
by report volume (all reactions)
15
reports citing this reaction
33.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. ENUCLEATION has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to ENUCLEATION changes

FDA AER · VeDDRA plate

Code 93098 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 15 reports
  • DEATH-HOT 33.3%
  • BOTTOM-DECILE #2298/2481
  • PHOTO-FINISH Abomasal ulcer
  • SPECIES-DOG Dog · 14
  • DRUG-LEAD Enrofloxacin · 8
  • DESK-WIDE 10 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abomasal ulcer (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around ENUCLEATION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abomasal ulcer · near15Burning sensation of… · near15Chronic hepatitis · near15Conjunctival haemorrh… · near15ENUCLEATION · this reaction15Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around ENUCLEATION

ENUCLEATION: high death-coded share in the FDA AER plate

Signature read: 15 reports place ENUCLEATION in the lower third of FDA AER volume (#2298 of 2,481). Report volume is lower-third scale: 15 named reports in the openFDA extract. Death-coded share is upper-third: 5 of 15 reports (33.3% of named reports). Nearest volume peer: Abomasal ulcer (±0 reports). Lead species Dog (14). Lead co-reported drug Enrofloxacin (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14
Horse 1

Breeds Most Affected

Terrier - Rat 3
Dog (unknown) 2
Chihuahua 2
Pug 2
Beagle 1
Dachshund (unspecified) 1
Spitz - German Pomeranian 1
Terrier - Boston 1
Quarter Horse 1
Crossbred Canine/dog 1

Associated Drugs

Enrofloxacin 8
Maropitant Citrate 6
Fluids 6
Carprofen 4
Prednisone 4
Tramadol 4
Trilostane 3
Salicylic Acid 3
Bacitracin/Neomycin/Polymixin B 3
Atropine 3
Serum 3
Cyclosporine 3
Eye Lubricant 3
Ofloxacin 3
Famotidine 3
Omiprazole 3
Capromorelin 3
Buprenorphine 3
Unknown Fluids 3
Metronidzaole 3

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for ENUCLEATION (#2298 of 2,481 by report volume); death-coded 33.3%. PlainBreed reaction plate · report volume stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →