Reaction profile

The FDA adverse-event record for walking on tiptoes

24 FDA reports name walking on tiptoes, a lower-volume reaction in the CVM extract (VeDDRA 2389). Plate stamps and neighbourhood peers follow.

#2101 of 2,481
by report volume (all reactions)
24
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Walking on tiptoes has 24 reports now versus 22 in that prior snapshot: 2 more (9.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
−1.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Walking on tiptoes changes

FDA AER · VeDDRA plate

Code 2389 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 24 reports
  • DEATH-ELEV 16.7%
  • LOWER-Q #2101/2481
  • PHOTO-FINISH Acute pancreatitis
  • SPECIES-DOG Dog · 15
  • DRUG-LEAD Ivermectin + Pyra… · 3
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acute pancreatitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Walking on tiptoes

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Acute pancreatitis · near24Application site para… · near24Cardiac tamponade · near24Eyelid ptosis - neuro… · near24Walking on tiptoes · this re…24Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Walking on tiptoes

What the FDA AER plate says about Walking on tiptoes

Signature read: 24 reports place Walking on tiptoes in the lower third of FDA AER volume (#2101 of 2,481). Report volume is lower-third scale: 24 named reports in the openFDA extract. 4 of 24 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Acute pancreatitis (±0 reports). Lead species Dog (15). Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 15
Cat 8
Horse 1

Breeds Most Affected

Domestic Shorthair 6
Retriever - Labrador 4
Shepherd Dog - Australian 2
Rottweiler 1
Warmblood - Swedish 1
Retriever - Golden 1
Pit Bull 1
Crossbred Canine/dog 1
Cat (unknown) 1
Scottish Fold Shorthair 1

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 3
Pyrantel Pamoate;Sarolaner 3
Maropitant Citrate 3
Gabapentin 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Buprenorphine 2
Melarsomine Dihydrochloride 2
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 2
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2
Imidacloprid + Moxidectin 2
Grapiprant 2
Moxidectin 1
Glucosamine 1
Canine Rabies Vaccine 1
Canine Vaccine 1
Caninie Vaccine 1
Fluralaner 1
Clodronate Disodium 1
Sarolaner 1
Milbemycin/Praziquantel 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Walking on tiptoes (#2101 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · report volume stamp 24 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →