Reaction profile

The FDA adverse-event record for barking

498 FDA adverse-event reports reference barking (VeDDRA 132). See the species, breeds, and drugs most associated with it below.

498
reports citing this reaction
7.6%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
498
Total Reports
38
Deaths
7.6%
Death Rate

Species Most Affected

Dog 498

Breeds Most Affected

Retriever - Labrador 46
Crossbred Canine/dog 39
Dog (unknown) 31
Retriever - Golden 25
Shih Tzu 22
Shepherd Dog - German 20
Chihuahua 17
Terrier - Yorkshire 12
Pit Bull 12
Shepherd Dog - Australian 12

Associated Drugs

Bedinvetmab 44
Oclacitinib Maleate 43
Milbemycin Oxime + Spinosad 38
Afoxolaner 36
Pyrantel Pamoate;Sarolaner 36
Trilostane 32
Carprofen 27
Spinosad 21
Fluralaner 13.64% 12-Week Chew 20
Fluralaner Chew Tablets 19
Gabapentin 19
Milbemycin Oxime + Praziquantel 19
Ivermectin + Pyrantel As Pamoate Salt 17
Fenbendazol Granules 17
Lotilaner 15
Prednisone 14
Sarolaner 13
Febantel + Praziquantel + Pyrantel Pamoate 12
Grapiprant 12
Imidacloprid + Moxidectin 11

Barking Reaction Insights

498 reports name Barking; 38 recorded a death outcome (7.6% of reported events, not a population-level mortality rate). VeDDRA code: 132.

By species: Dog (498 reports). By breed: Retriever - Labrador (46), Crossbred Canine/dog (39), Dog (unknown) (31).

Most co-reported drugs: Bedinvetmab (44 reports), Oclacitinib Maleate (43 reports), Milbemycin Oxime + Spinosad (38 reports), Afoxolaner (36 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.