Reaction profile

The FDA adverse-event record for haemorrhage nos

774 FDA adverse-event reports reference haemorrhage nos (VeDDRA 177). See the species, breeds, and drugs most associated with it below.

774
reports citing this reaction
52.5%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
774
Total Reports
406
Deaths
52.5%
Death Rate

Species Most Affected

Dog 585
Cat 128
Cattle 26
Horse 13
Human 7
Other Birds 3
Unknown 2
Pig 2
Chicken 2
Other Equids 2

Breeds Most Affected

Retriever - Labrador 62
Domestic Shorthair 55
Crossbred Canine/dog 39
Dog (unknown) 36
Shepherd Dog - German 34
Retriever - Golden 25
Domestic (unspecified) 24
Boxer (German Boxer) 22
Dachshund (unspecified) 17
Beagle 17

Associated Drugs

Carprofen 102
Milbemycin Oxime + Spinosad 76
Maropitant Citrate 54
Oclacitinib Maleate 49
Cefovecin 37
Spinosad 33
Moxidectin 29
Selamectin 29
Meloxicam 28
Buprenorphine 28
Bedinvetmab 27
Prednisone 24
Afoxolaner 24
Butorphanol 23
Dexmedetomidine Hydrochloride 21
Isoflurane 21
Polysulfated Glycosaminoglycan 21
Robenacoxib 20
Tramadol 19
Fluralaner Chew Tablets 19

Haemorrhage NOS Reaction Insights

774 reports name Haemorrhage NOS; 406 recorded a death outcome (52.5% of reported events, not a population-level mortality rate). VeDDRA code: 177.

By species: Dog (585 reports), Cat (128 reports), Cattle (26 reports). By breed: Retriever - Labrador (62), Domestic Shorthair (55), Crossbred Canine/dog (39).

Most co-reported drugs: Carprofen (102 reports), Milbemycin Oxime + Spinosad (76 reports), Maropitant Citrate (54 reports), Oclacitinib Maleate (49 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.