Reaction profile

The FDA adverse-event record for obtunded

Name: Obtunded - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

141 FDA adverse-event reports reference obtunded (VeDDRA 3108). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1224 of 2,481
by report volume (all reactions): 141
reports citing this reaction: 59.6%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Obtunded has 141 reports now versus 117 in that prior snapshot: 24 more (20.5%).

Report change: +24
Death-coded reports: +7
Death-coded share: −6.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Obtunded changes

FDA AER · VeDDRA plate

Code 3108 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-LOW 141 reports
DEATH-HOT 59.6%
MID-PACK #1224/2481
PHOTO-FINISH Skin reaction NOS
SPECIES-DOG Dog · 95
DRUG-LEAD Maropitant Citrate · 34
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Skin reaction NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Obtunded

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

FDA AER report volume · neighbourhood around Obtunded

Obtunded: high death-coded share in the FDA AER plate

Signature read: Obtunded's 59.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 84 of 141 reports (59.6% of named reports). Nearest volume peer: Skin reaction NOS (±0 reports). Lead species Dog (95). Lead co-reported drug Maropitant Citrate (34).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 95

Cat 46

Breeds Most Affected

Domestic Shorthair 35

Retriever - Labrador 14

Crossbred Canine/dog 8

Shepherd Dog - Australian 6

Retriever - Golden 5

Chihuahua 5

Pug 3

Cat (unknown) 3

Bulldog - French 3

Domestic (unspecified) 3

Associated Drugs

Maropitant Citrate 34

Bedinvetmab 33

Gabapentin 25

Carprofen 15

Buprenorphine 15

Fluid Therapy 12

Prednisone 11

Metronidazole 9

Eprinomectin + Esafoxolaner + Praziquantel 9

Meloxicam 8

Robenacoxib 8

Isoflurane 8

Naloxone 7

Capromorelin 7

Butorphanol 6

Propofol 6

Ondansetron 6

Velagliflozin Proline Monohydrate 6

Galliprant 6

Oclacitinib Maleate 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Obtunded, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (141 here).

Skin reaction NOS 141 Dehiscence, medical device 140 Difficulty eating NOS 142 Involuntary urination 142

Similar death-coded share

Nearest other reactions by death-coded share (59.6% here), distinct from the volume row.

Respiratory distress 59.6% Heart failure 59.7% Nephritis 60.6% Peritonitis 58.6%

What to do with this reaction

Compare Obtunded's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Obtunded (#1224 of 2,481 by report volume); death-coded 59.6%. PlainBreed reaction plate · death-coded share stamp 59.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →