Reaction profile

The FDA adverse-event record for bloated stomach

269 FDA adverse-event reports reference bloated stomach (VeDDRA 1351). See the species, breeds, and drugs most associated with it below.

269
reports citing this reaction
28.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
269
Total Reports
76
Deaths
28.3%
Death Rate

Species Most Affected

Dog 234
Cat 22
Human 5
Cattle 3
Horse 2
Pig 2
Goat 1

Breeds Most Affected

Retriever - Labrador 24
Crossbred Canine/dog 16
Chihuahua 16
Retriever - Golden 15
Terrier - Yorkshire 13
Terrier - Jack Russell 9
Pit Bull 8
Domestic Shorthair 7
Beagle 7
Shepherd Dog - German 7

Associated Drugs

Milbemycin Oxime + Spinosad 41
Trilostane 20
Maropitant Citrate 20
Carprofen 16
Afoxolaner 15
Gabapentin 14
Fluralaner Chew Tablets 13
Deracoxib 11
Milbemycin Oxime + Praziquantel 11
Oclacitinib Maleate 11
Metronidazole 10
Lotilaner 10
Spinosad 9
Polysulfated Glycosaminoglycan 9
Pantoprazole 9
Ivermectin + Pyrantel As Pamoate Salt 9
Fluralaner 13.64% 12-Week Chew 9
Bedinvetmab 9
Metoclopramide 8
Ondansetron 8

Bloated stomach Reaction Insights

269 reports name Bloated stomach; 76 recorded a death outcome (28.3% of reported events, not a population-level mortality rate). VeDDRA code: 1351.

By species: Dog (234 reports), Cat (22 reports), Human (5 reports). By breed: Retriever - Labrador (24), Crossbred Canine/dog (16), Chihuahua (16).

Most co-reported drugs: Milbemycin Oxime + Spinosad (41 reports), Trilostane (20 reports), Maropitant Citrate (20 reports), Carprofen (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.