Reaction profile

The FDA adverse-event record for allergic oedema

74 FDA adverse-event reports reference allergic oedema (VeDDRA 515). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1542 of 2,481
by report volume (all reactions)
74
reports citing this reaction
4.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Allergic oedema has 74 reports now versus 74 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Allergic oedema changes

FDA AER · VeDDRA plate

Code 515 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 74 reports
  • DEATH-LOW 4.1%
  • MID-PACK #1542/2481
  • PHOTO-FINISH Abnormal tail posture
  • SPECIES-DOG Dog · 50
  • DRUG-LEAD Moxidectin · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal tail posture (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Allergic oedema

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abnormal tail posture · near74Allergic oedema · this react…74Bronchopulmonary infl… · near74Cervical ventroflexion · near74Coughing blood · near74Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Allergic oedema

Allergic oedema: low death-coded share in the FDA AER plate

Signature read: 3 death-coded reports is a thin tail count for Allergic oedema in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 3 of 74 reports (4.1% of named reports). Nearest volume peer: Abnormal tail posture (±0 reports). Lead species Dog (50). Lead co-reported drug Moxidectin (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 50
Horse 13
Human 4
Cattle 3
Cat 3
Bat 1

Breeds Most Affected

Unknown 7
Retriever - Labrador 6
Quarter Horse 5
Shepherd Dog - Australian 4
Dachshund (unspecified) 4
Chihuahua 3
Mixed (Dog) 3
Boxer (German Boxer) 3
Horse (unknown) 3
Weimaraner 2

Associated Drugs

Moxidectin 14
Isoflurane 6
Milbemycin Oxime + Spinosad 5
Butorphanol 4
Fluralaner 13.64% 12-Week Chew 4
Imidacloprid + Moxidectin 3
Carprofen 3
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 3
Polysulfated Glycosaminoglycan 3
Afoxolaner 3
Diphenhydramine 3
Fluralaner Spot-On Solution 3
Alfaxalone 3
Praziquantel;Moxidectin 3
Melarsomine 2
Glycosaminoglycan Polysulfate 2
Enrofloxacin 2
Ceftiofur Crystalline Free Acid 2
Borrelia Burgdorferi Strain Ips 930-34-081596; Borrelia Burgdorferi Strain B-31 2
Spinosad 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Allergic oedema, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (74 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Allergic oedema (#1542 of 2,481 by report volume); death-coded 4.1%. PlainBreed reaction plate · death-coded report count stamp 3 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →