Reaction profile

The FDA adverse-event record for pr-joint(s), lesion(s)

Name: PR-JOINT(S), LESION(S) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

10 FDA reports name pr-joint(s), lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99624). Plate stamps and neighbourhood peers follow.

#2469 of 2,481
by report volume (all reactions): 10
reports citing this reaction: 80.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-JOINT(S), LESION(S) has 10 reports now versus 10 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-JOINT(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99624 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 10 reports
DEATH-HOT 80.0%
BOTTOM-DECILE #2469/2481
PHOTO-FINISH Anoxia
SPECIES-DOG Dog · 4
DRUG-LEAD Tulathromycin · 2
DESK-WIDE 9 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-JOINT, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around PR-JOINT(S), LESION(S)

PR-JOINT(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: 10 reports place PR-JOINT(S), LESION(S) in the lower third of FDA AER volume (#2469 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. Death-coded share is upper-third: 8 of 10 reports (80.0% of named reports). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (4). Lead co-reported drug Tulathromycin (2).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 4

Cattle 2

Horse 2

Cat 1

Pig 1

Breeds Most Affected

Cattle (other) 2

Retriever - Labrador 1

Schnauzer (unspecified) 1

Domestic Longhair 1

Hound - Basset 1

Pig (unknown) 1

Thoroughbred 1

Retriever - Golden 1

Unknown 1

Associated Drugs

Tulathromycin 2

Lufenuron + Milbemycin Oxime 1

Trilostane 1

Milk Thistle 1

Symptom Remedy 1

Remania 8 1

Pro Neurizine 1

Cefovecin 1

Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str 1

Ceftiofur Crystalline Free Acid 1

Oclacitinib Maleate 1

Selegiline Hcl 1

Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 1

Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 1

Doramectin 1

Ractopamine 1

Pergolide Mesylate 1

Grapiprant 1

Sodium Hyaluronate 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-JOINT(S), LESION(S) (#2469 of 2,481 by report volume); death-coded 80.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →